Meta-analysis of the risk of small bowel obstruction following open or laparoscopic colorectal surgery

T. Yamada, Koji Okabayashi, H. Hasegawa, Masashi Tsuruta, J. H. Yoo, Ryo Seishima, Yuukou Kitagawa

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20 Citations (Scopus)


Background: One of the potential advantages of laparoscopic compared with open colorectal surgery is a reduction in postoperative bowel obstruction events. Early reports support this proposal, but accumulated evidence is lacking. Methods: A systematic review and meta-analysis was performed of randomized clinical trials and observational studies by searching the PubMed and Cochrane Library databases from 1990 to August 2015. The primary outcomes were early and late postoperative bowel obstruction following laparoscopic and open colorectal surgery. Both ileus and bowel obstruction were defined as a postoperative bowel obstruction. Subgroup and sensitivity analyses were performed, and a random-effects model was used to account for the heterogeneity among the studies. Results: Twenty-four randomized clinical trials and 88 observational studies were included in the meta-analysis; 106 studies reported early outcome and 12 late outcome. Collectively, these studies reported on the outcomes of 148392 patients, of whom 58133 had laparoscopic surgery and 90259 open surgery. Compared with open surgery, laparoscopic surgery was associated with reduced rates of early (odds ratio 0·62, 95 per cent c.i. 0·54 to 0·72; P

Original languageEnglish
JournalBritish Journal of Surgery
Publication statusAccepted/In press - 2016


ASJC Scopus subject areas

  • Surgery

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