Metabolic syndrome

Masanori Mitsuishi, Kazutoshi Miyashita, Hiroshi Itoh

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Metabolic syndrome, which is consisted of hypertension, dyslipidemia and impaired glucose tolerance, is one of the most significant lifestyle-related disorders that lead to cardiovascular diseases. Among many upstream factors that are related to metabolic syndrome, obesity, especially visceral obesity, plays an essential role in its pathogenesis. In recent studies, possible mechanisms which connect obesity to metabolic syndrome have been elucidated, such as inflammation, abnormal secretion of adipokines and mitochondrial dysfunction. In this review, we focus on the relationship between obesity and metabolic syndrome; and illustrate how visceral obesity contributes to, and how the treatments for obesity act on metabolic syndrome.

Original languageEnglish
Pages (from-to)321-326
Number of pages6
JournalNippon rinsho. Japanese journal of clinical medicine
Volume67
Issue number2
Publication statusPublished - 2009 Feb

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Mitsuishi, M., Miyashita, K., & Itoh, H. (2009). Metabolic syndrome. Nippon rinsho. Japanese journal of clinical medicine, 67(2), 321-326.