Metachronous gastric carcinoma from a gastric tube after radical surgery for esophageal carcinoma

Nobuhiko Okamoto, Soji Ozawa, Yuukou Kitagawa, Yoshimasa Shimizu, Masaki Kitajima

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Background Cases of metachronous gastric carcinoma arising from a gastric tube used for reconstruction have been increasing in long-term survivors of esophageal cancer in recent years. We investigated the characteristics of gastric tube carcinoma to determine the most appropriate approach to managing it. Methods Between 1980 and 1997, 508 patients underwent radical esophagectomy for esophageal carcinoma at Keio University Hospital. Reconstruction was performed with a gastric tube in 414 (81.5%) of them, and 8 of them developed a metachronous carcinoma in the gastric tube. The clinical and pathologic characteristics of the gastric tube carcinomas were evaluated in this study. Results Gastric cancer was detected during follow-up endoscopic examinations or in an upper gastrointestinal series in seven patients. All of the cancers were diagnosed as adenocarcinoma histopathologically. Endoscopic mucosal resection was performed in two patients, partial resection of the residual stomach was performed in three patients. One patient was treated by endoscopic mucosal resection as palliative therapy, since he had severe pulmonary emphysema. Total resection of the gastric tube was attempted in 2 advanced cases but was unsuccessful because of direct invasion of other organ by the cancer. The 5 patients who underwent curative resection are alive with no subsequent recurrence. Conclusions Since early diagnosis permits less invasive treatment and curative treatment is difficult in advanced cases, strict postoperative examinations are important after radical esophagectomy to ensure early detection of metachronous gastric carcinoma arising from gastric tubes used for reconstruction.

Original languageEnglish
Pages (from-to)1189-1192
Number of pages4
JournalAnnals of Thoracic Surgery
Volume77
Issue number4
DOIs
Publication statusPublished - 2004 Apr

Fingerprint

Stomach
Carcinoma
Esophagectomy
Gastric Stump
Pulmonary Emphysema
Esophageal Neoplasms
Palliative Care
Stomach Neoplasms
Survivors
Early Diagnosis
Neoplasms
Adenocarcinoma
Recurrence
Therapeutics

Keywords

  • 7

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Metachronous gastric carcinoma from a gastric tube after radical surgery for esophageal carcinoma. / Okamoto, Nobuhiko; Ozawa, Soji; Kitagawa, Yuukou; Shimizu, Yoshimasa; Kitajima, Masaki.

In: Annals of Thoracic Surgery, Vol. 77, No. 4, 04.2004, p. 1189-1192.

Research output: Contribution to journalArticle

Okamoto, Nobuhiko ; Ozawa, Soji ; Kitagawa, Yuukou ; Shimizu, Yoshimasa ; Kitajima, Masaki. / Metachronous gastric carcinoma from a gastric tube after radical surgery for esophageal carcinoma. In: Annals of Thoracic Surgery. 2004 ; Vol. 77, No. 4. pp. 1189-1192.
@article{6649898403214b7da5d16b1939dda840,
title = "Metachronous gastric carcinoma from a gastric tube after radical surgery for esophageal carcinoma",
abstract = "Background Cases of metachronous gastric carcinoma arising from a gastric tube used for reconstruction have been increasing in long-term survivors of esophageal cancer in recent years. We investigated the characteristics of gastric tube carcinoma to determine the most appropriate approach to managing it. Methods Between 1980 and 1997, 508 patients underwent radical esophagectomy for esophageal carcinoma at Keio University Hospital. Reconstruction was performed with a gastric tube in 414 (81.5{\%}) of them, and 8 of them developed a metachronous carcinoma in the gastric tube. The clinical and pathologic characteristics of the gastric tube carcinomas were evaluated in this study. Results Gastric cancer was detected during follow-up endoscopic examinations or in an upper gastrointestinal series in seven patients. All of the cancers were diagnosed as adenocarcinoma histopathologically. Endoscopic mucosal resection was performed in two patients, partial resection of the residual stomach was performed in three patients. One patient was treated by endoscopic mucosal resection as palliative therapy, since he had severe pulmonary emphysema. Total resection of the gastric tube was attempted in 2 advanced cases but was unsuccessful because of direct invasion of other organ by the cancer. The 5 patients who underwent curative resection are alive with no subsequent recurrence. Conclusions Since early diagnosis permits less invasive treatment and curative treatment is difficult in advanced cases, strict postoperative examinations are important after radical esophagectomy to ensure early detection of metachronous gastric carcinoma arising from gastric tubes used for reconstruction.",
keywords = "7",
author = "Nobuhiko Okamoto and Soji Ozawa and Yuukou Kitagawa and Yoshimasa Shimizu and Masaki Kitajima",
year = "2004",
month = "4",
doi = "10.1016/j.athoracsur.2003.09.071",
language = "English",
volume = "77",
pages = "1189--1192",
journal = "Annals of Thoracic Surgery",
issn = "0003-4975",
publisher = "Elsevier USA",
number = "4",

}

TY - JOUR

T1 - Metachronous gastric carcinoma from a gastric tube after radical surgery for esophageal carcinoma

AU - Okamoto, Nobuhiko

AU - Ozawa, Soji

AU - Kitagawa, Yuukou

AU - Shimizu, Yoshimasa

AU - Kitajima, Masaki

PY - 2004/4

Y1 - 2004/4

N2 - Background Cases of metachronous gastric carcinoma arising from a gastric tube used for reconstruction have been increasing in long-term survivors of esophageal cancer in recent years. We investigated the characteristics of gastric tube carcinoma to determine the most appropriate approach to managing it. Methods Between 1980 and 1997, 508 patients underwent radical esophagectomy for esophageal carcinoma at Keio University Hospital. Reconstruction was performed with a gastric tube in 414 (81.5%) of them, and 8 of them developed a metachronous carcinoma in the gastric tube. The clinical and pathologic characteristics of the gastric tube carcinomas were evaluated in this study. Results Gastric cancer was detected during follow-up endoscopic examinations or in an upper gastrointestinal series in seven patients. All of the cancers were diagnosed as adenocarcinoma histopathologically. Endoscopic mucosal resection was performed in two patients, partial resection of the residual stomach was performed in three patients. One patient was treated by endoscopic mucosal resection as palliative therapy, since he had severe pulmonary emphysema. Total resection of the gastric tube was attempted in 2 advanced cases but was unsuccessful because of direct invasion of other organ by the cancer. The 5 patients who underwent curative resection are alive with no subsequent recurrence. Conclusions Since early diagnosis permits less invasive treatment and curative treatment is difficult in advanced cases, strict postoperative examinations are important after radical esophagectomy to ensure early detection of metachronous gastric carcinoma arising from gastric tubes used for reconstruction.

AB - Background Cases of metachronous gastric carcinoma arising from a gastric tube used for reconstruction have been increasing in long-term survivors of esophageal cancer in recent years. We investigated the characteristics of gastric tube carcinoma to determine the most appropriate approach to managing it. Methods Between 1980 and 1997, 508 patients underwent radical esophagectomy for esophageal carcinoma at Keio University Hospital. Reconstruction was performed with a gastric tube in 414 (81.5%) of them, and 8 of them developed a metachronous carcinoma in the gastric tube. The clinical and pathologic characteristics of the gastric tube carcinomas were evaluated in this study. Results Gastric cancer was detected during follow-up endoscopic examinations or in an upper gastrointestinal series in seven patients. All of the cancers were diagnosed as adenocarcinoma histopathologically. Endoscopic mucosal resection was performed in two patients, partial resection of the residual stomach was performed in three patients. One patient was treated by endoscopic mucosal resection as palliative therapy, since he had severe pulmonary emphysema. Total resection of the gastric tube was attempted in 2 advanced cases but was unsuccessful because of direct invasion of other organ by the cancer. The 5 patients who underwent curative resection are alive with no subsequent recurrence. Conclusions Since early diagnosis permits less invasive treatment and curative treatment is difficult in advanced cases, strict postoperative examinations are important after radical esophagectomy to ensure early detection of metachronous gastric carcinoma arising from gastric tubes used for reconstruction.

KW - 7

UR - http://www.scopus.com/inward/record.url?scp=1842427955&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1842427955&partnerID=8YFLogxK

U2 - 10.1016/j.athoracsur.2003.09.071

DO - 10.1016/j.athoracsur.2003.09.071

M3 - Article

VL - 77

SP - 1189

EP - 1192

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

SN - 0003-4975

IS - 4

ER -