Microbial production of (2 R, 4 R)-2,4-pentanediol by enatioselective reduction of acetylacetone and stereoinversion of 2,4-pentanediol

Shuichi Matsumura, Yoko Kawai, Yoshinori Takahashi, Kazunobu Toshima

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(2 R, 4 R)-2,4-Pentanediol was obtained by the enatioselective reduction of acetylacetone (2,4-pentanedione) with the resting cells of methanol yeast, Candida boidinii KK912 (IFO 10574). (2 R, 4 R)-2,4-Pentanediol was also obtained by the stereoinversion of the isomeric mixture of 2,4-pentanediol.

Original languageEnglish
Pages (from-to)485-490
Number of pages6
JournalBiotechnology Letters
Issue number5
Publication statusPublished - 1994 May 1


ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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