Microbial transformation of dehydrogriseofulvin and griseofulvin: 2H n.m.r. and mass spectrometric studies of stereochemical courses of microbial hydrogenation and hydroxylation

Yoshiriro Sato, Taiko Oda, Hazime Saitô

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23 Citations (Scopus)

Abstract

2H N.m.r. spectroscopy has been used to determine the stereochemistry of microbial hydrogenation of dehydrogriseofulvin to griseofulvin and microbial hydroxylation of the latter to 5′α- hydroxygriseofulvin, respectively.

Original languageEnglish
Pages (from-to)415-417
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number12
DOIs
Publication statusPublished - 1977

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Griseofulvin
Hydroxylation
Stereochemistry
Hydrogenation
Spectrum Analysis
Spectroscopy
dehydrogriseofulvin

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

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title = "Microbial transformation of dehydrogriseofulvin and griseofulvin: 2H n.m.r. and mass spectrometric studies of stereochemical courses of microbial hydrogenation and hydroxylation",
abstract = "2H N.m.r. spectroscopy has been used to determine the stereochemistry of microbial hydrogenation of dehydrogriseofulvin to griseofulvin and microbial hydroxylation of the latter to 5′α- hydroxygriseofulvin, respectively.",
author = "Yoshiriro Sato and Taiko Oda and Hazime Sait{\^o}",
year = "1977",
doi = "10.1039/C39770000415",
language = "English",
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journal = "Chemical Communications",
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publisher = "Royal Society of Chemistry",
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T2 - 2H n.m.r. and mass spectrometric studies of stereochemical courses of microbial hydrogenation and hydroxylation

AU - Sato, Yoshiriro

AU - Oda, Taiko

AU - Saitô, Hazime

PY - 1977

Y1 - 1977

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AB - 2H N.m.r. spectroscopy has been used to determine the stereochemistry of microbial hydrogenation of dehydrogriseofulvin to griseofulvin and microbial hydroxylation of the latter to 5′α- hydroxygriseofulvin, respectively.

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JO - Chemical Communications

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