Microbial transformation of dehydrogriseofulvin and griseofulvin: 2H n.m.r. and mass spectrometric studies of stereochemical courses of microbial hydrogenation and hydroxylation

Yoshiriro Sato, Taiko Oda, Hazime Saitô

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Abstract

2H N.m.r. spectroscopy has been used to determine the stereochemistry of microbial hydrogenation of dehydrogriseofulvin to griseofulvin and microbial hydroxylation of the latter to 5′α- hydroxygriseofulvin, respectively.

Original languageEnglish
Pages (from-to)415-417
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number12
DOIs
Publication statusPublished - 1977 Dec 1

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ASJC Scopus subject areas

  • Molecular Medicine

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