Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes

Mariana Medina-Sánchez, Carmen C. Mayorga-Martinez, Takeshi Watanabe, Tribidasari A. Ivandini, Yuki Honda, Flavio Pino, Azuya Nakata, Akira Fujishima, Yasuaki Einaga, Arben Merkoçi

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

We have developed a lab-on-a-chip (LOC) platform for electrochemical detection and degradation of the pesticide atrazine (Atz). It is based on boron-doped diamond (BDD) electrodes and a competitive magneto-enzyme immunoassay (EIA) that enables high sensitivity. To detect the enzymatic reaction, we employed a BDD electrode modified with platinum nanoparticles (PtNPs), as a highly conductive catalytic transducer. Chronoamperometry revealed a limit of detection (LOD) of 3.5pM for atrazine, which, to the best of our knowledge, is one of the lowest value published to date. Finally, we degraded Atz in the same platform, using a bare BDD electrode that features remarkable corrosion stability, a wide potential window, and much higher O<inf>2</inf> overvoltage as compared to conventional electrodes. These characteristics enable the electrode to produce a greater amount of HO<sup>•</sup> on the anode surface than do conventional electrodes and consequently, to destroy the pollutant more rapidly. Our new LOC platform might prove interesting as a smart system for detection and remediation of diverse pesticides and other contaminants.

Original languageEnglish
Article number7954
Pages (from-to)365-374
Number of pages10
JournalBiosensors and Bioelectronics
Volume75
DOIs
Publication statusPublished - 2016 Jan 15

Fingerprint

Diamond
Boron
Microfluidics
Diamonds
Electrodes
Impurities
Atrazine
Degradation
Herbicides
Lab-on-a-chip
Pesticides
Chronoamperometry
Platinum
Corrosion
Remediation
Transducers
Immunoenzyme Techniques
Anodes
Nanoparticles
Enzymes

Keywords

  • Atrazine degradation
  • Atrazine detection
  • Biosensor
  • Boron-doped diamond electrode
  • Microfluidics
  • Platinum nanostructured particles

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Biotechnology
  • Electrochemistry

Cite this

Medina-Sánchez, M., Mayorga-Martinez, C. C., Watanabe, T., Ivandini, T. A., Honda, Y., Pino, F., ... Merkoçi, A. (2016). Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes. Biosensors and Bioelectronics, 75, 365-374. [7954]. https://doi.org/10.1016/j.bios.2015.08.058

Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes. / Medina-Sánchez, Mariana; Mayorga-Martinez, Carmen C.; Watanabe, Takeshi; Ivandini, Tribidasari A.; Honda, Yuki; Pino, Flavio; Nakata, Azuya; Fujishima, Akira; Einaga, Yasuaki; Merkoçi, Arben.

In: Biosensors and Bioelectronics, Vol. 75, 7954, 15.01.2016, p. 365-374.

Research output: Contribution to journalArticle

Medina-Sánchez, M, Mayorga-Martinez, CC, Watanabe, T, Ivandini, TA, Honda, Y, Pino, F, Nakata, A, Fujishima, A, Einaga, Y & Merkoçi, A 2016, 'Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes', Biosensors and Bioelectronics, vol. 75, 7954, pp. 365-374. https://doi.org/10.1016/j.bios.2015.08.058
Medina-Sánchez, Mariana ; Mayorga-Martinez, Carmen C. ; Watanabe, Takeshi ; Ivandini, Tribidasari A. ; Honda, Yuki ; Pino, Flavio ; Nakata, Azuya ; Fujishima, Akira ; Einaga, Yasuaki ; Merkoçi, Arben. / Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes. In: Biosensors and Bioelectronics. 2016 ; Vol. 75. pp. 365-374.
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