Migratory pathways of GABAergic interneurons when they enter the neocortex

Daisuke H. Tanaka, Kazunori Nakajima

Research output: Contribution to journalReview article

27 Citations (Scopus)

Abstract

Inhibitory gamma-aminobutyric-acid-containing interneurons play important roles in the functions of the neocortex. During rodent development, most neocortical interneurons are generated in the subpallium and migrate tangentially toward the neocortex. They migrate through multiple pathways to enter the neocortex. Failure of interneuron migration through these pathways during development leads to an abnormal distribution and abnormal functions of interneurons in the postnatal brain. Because of recent discoveries regarding the novel origins and migratory pathways of neocortical interneurons, in this article we review the literature on the migratory pathways of interneurons when they enter the neocortex.

Original languageEnglish
Pages (from-to)1655-1660
Number of pages6
JournalEuropean Journal of Neuroscience
Volume35
Issue number11
DOIs
Publication statusPublished - 2012 Jun 1

Keywords

  • Cerebral cortex
  • Development
  • Migration
  • Rodent

ASJC Scopus subject areas

  • Neuroscience(all)

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