Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly

Midori Kato-Negishi; Yuya Morimoto; Hiroaki Onoe; Shoji Takeuchi

doi:10.1002/adhm.201300052

Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly

Midori Kato-Negishi, Yuya Morimoto, Hiroaki Onoe, Shoji Takeuchi

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.

Original language	English
Pages (from-to)	1564-1570
Number of pages	7
Journal	Advanced Healthcare Materials
Volume	2
Issue number	12
DOIs	https://doi.org/10.1002/adhm.201300052
Publication status	Published - 2013 Dec
Externally published	Yes

Keywords

Assembly
Cortex
Hippocampus
Neural network
Three-dimensional neural tissue

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Pharmaceutical Science

Access to Document

10.1002/adhm.201300052

Fingerprint Dive into the research topics of 'Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly'. Together they form a unique fingerprint.

Cite this

@article{4d18cc68b4ad497aa958de08df15499f,

title = "Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly",

abstract = "A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.",

keywords = "Assembly, Cortex, Hippocampus, Neural network, Three-dimensional neural tissue",

author = "Midori Kato-Negishi and Yuya Morimoto and Hiroaki Onoe and Shoji Takeuchi",

year = "2013",

month = dec,

doi = "10.1002/adhm.201300052",

language = "English",

volume = "2",

pages = "1564--1570",

journal = "Advanced healthcare materials",

issn = "2192-2640",

publisher = "John Wiley and Sons Ltd",

number = "12",

}

TY - JOUR

T1 - Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly

AU - Kato-Negishi, Midori

AU - Morimoto, Yuya

AU - Onoe, Hiroaki

AU - Takeuchi, Shoji

PY - 2013/12

Y1 - 2013/12

N2 - A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.

AB - A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.

KW - Assembly

KW - Cortex

KW - Hippocampus

KW - Neural network

KW - Three-dimensional neural tissue

UR - http://www.scopus.com/inward/record.url?scp=84889649651&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889649651&partnerID=8YFLogxK

U2 - 10.1002/adhm.201300052

DO - 10.1002/adhm.201300052

M3 - Article

C2 - 23828857

AN - SCOPUS:84889649651

VL - 2

SP - 1564

EP - 1570

JO - Advanced healthcare materials

JF - Advanced healthcare materials

SN - 2192-2640

IS - 12

ER -