Abstract
A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.
| Original language | English |
|---|---|
| Pages (from-to) | 1564-1570 |
| Number of pages | 7 |
| Journal | Advanced healthcare materials |
| Volume | 2 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2013 Dec |
| Externally published | Yes |
Fingerprint
Keywords
- Assembly
- Cortex
- Hippocampus
- Neural network
- Three-dimensional neural tissue
ASJC Scopus subject areas
- Biomedical Engineering
- Biomaterials
- Pharmaceutical Science
Cite this
Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly. / Kato-Negishi, Midori; Morimoto, Yuya; Onoe, Hiroaki; Takeuchi, Shoji.
In: Advanced healthcare materials, Vol. 2, No. 12, 12.2013, p. 1564-1570.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly
AU - Kato-Negishi, Midori
AU - Morimoto, Yuya
AU - Onoe, Hiroaki
AU - Takeuchi, Shoji
PY - 2013/12
Y1 - 2013/12
N2 - A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.
AB - A millimeter-sized neural building block (NBB) shows high versatility to form a 3D heterogeneous neural component. A millimeter-sized 3D neural network between heterogeneous neural tissues is established, and an efficient technique is then developed to observe the spatiotemporal metrological changes of single neuron in the NBB. This technique allows the visualization of axonal extension, dendritic branching, and morphological changes of presynaptic components and synapses in real time.
KW - Assembly
KW - Cortex
KW - Hippocampus
KW - Neural network
KW - Three-dimensional neural tissue
UR - http://www.scopus.com/inward/record.url?scp=84889649651&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84889649651&partnerID=8YFLogxK
U2 - 10.1002/adhm.201300052
DO - 10.1002/adhm.201300052
M3 - Article
VL - 2
SP - 1564
EP - 1570
JO - Advanced healthcare materials
JF - Advanced healthcare materials
SN - 2192-2640
IS - 12
ER -