miRNA regulatory ecosystem in early development

Research output: Contribution to journalShort surveypeer-review

3 Citations (Scopus)

Abstract

MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. (2014) now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis. MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis.

Original languageEnglish
Pages (from-to)615-616
Number of pages2
JournalMolecular Cell
Volume56
Issue number5
DOIs
Publication statusPublished - 2014 Dec 4

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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