miRNA regulatory ecosystem in early development

Yuka W. Iwasaki; Haruhiko Siomi

doi:10.1016/j.molcel.2014.11.010

miRNA regulatory ecosystem in early development

Yuka W. Iwasaki, Haruhiko Siomi

Department of Molecular Biology

Research output: Contribution to journal › Short survey › peer-review

5 Citations (Scopus)

Abstract

MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. (2014) now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis. MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis.

Original language	English
Pages (from-to)	615-616
Number of pages	2
Journal	Molecular Cell
Volume	56
Issue number	5
DOIs	https://doi.org/10.1016/j.molcel.2014.11.010
Publication status	Published - 2014 Dec 4

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2014.11.010

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title = "miRNA regulatory ecosystem in early development",

abstract = "MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. (2014) now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis. MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis.",

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year = "2014",

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AB - MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. (2014) now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis. MicroRNAs (miRNAs) reshape spatiotemporal gene expression by both modulating the levels of actively transcribed genes and accelerating the clearance of previously transcribed messages, thereby promoting the transition from a preceding stage to subsequent processes during development. Lee etal. now demonstrate that maternal miRNAs are adenylated by Wispy, which leads to clearing of maternal miRNAs during early embryogenesis.

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miRNA regulatory ecosystem in early development

Abstract

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