Model-based feedback control of synthetic biomolecular circuits

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The advance of synthetic biology has opened up many potential applications of synthetic biocircuits, including sensing, computation and high-value chemical production using biological cells. To enable rational and robust design of large-scale and complex systems, model-guided design of biocircuits has been increasingly important. Here we review a combined theoretical and experimental platform for model-based optimization of biocircuits. The framework combines feedback control theory and microfluidic technology to enable rapid characterization of biocircuit dynamics in vitro based on advanced mathematical tools in feedback control.

Original languageEnglish
Title of host publicationMHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1-2
Number of pages2
ISBN (Electronic)9781538633144
DOIs
Publication statusPublished - 2018 Feb 28
Event28th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2017 - Nagoya, Japan
Duration: 2017 Dec 32017 Dec 6

Publication series

NameMHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science
Volume2018-January

Other

Other28th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2017
CountryJapan
CityNagoya
Period17/12/317/12/6

ASJC Scopus subject areas

  • Biotechnology
  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Mechanical Engineering

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  • Cite this

    Hori, Y. (2018). Model-based feedback control of synthetic biomolecular circuits. In MHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science (pp. 1-2). (MHS 2017 - 28th 2017 International Symposium on Micro-NanoMechatronics and Human Science; Vol. 2018-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2017.8305288