Modeling of influence of frontal sinus on NIRS signal of brain activation

Daisuke Yamamoto, Shoko Kuroda, Eiji Okada

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    In the brain activation measurements by near infrared spectroscopy (NIRS), the partial optical path length in the brain, which is an index of the sensitivity of the NIRS signal to the brain activation, is strongly affected by the thickness and the structure of the superficial tissues. In this study, we investigate the influence of the frontal sinus on the NIRS signal of the brain activation. The light propagation in a simplified head model including a void region mimicking the frontal sinus is predicted by Monte Carlo simulation to investigate the influence of the frontal sinus on the partial optical path length in the brain and the mean optical path length in the head. The frontal sinus strongly affects the light propagation in the head. The partial optical path length for small source-detector separation tends to be increased by the presence of the frontal sinus whereas that for large source-detector separation is decreased by the influence of the frontal sinus.

    Original languageEnglish
    Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2007
    PublisherOptical Society of America
    ISBN (Print)9780819467713
    Publication statusPublished - 2007 Jan 1
    EventEuropean Conference on Biomedical Optics, ECBO 2007 - Munich, Germany
    Duration: 2007 Jun 172007 Jun 17

    Publication series

    NameOptics InfoBase Conference Papers
    ISSN (Electronic)2162-2701

    Other

    OtherEuropean Conference on Biomedical Optics, ECBO 2007
    CountryGermany
    CityMunich
    Period07/6/1707/6/17

    Keywords

    • Brain activation measurement
    • Frontal sinus
    • Near infrared spectroscopy
    • Partial optical path length

    ASJC Scopus subject areas

    • Instrumentation
    • Atomic and Molecular Physics, and Optics

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  • Cite this

    Yamamoto, D., Kuroda, S., & Okada, E. (2007). Modeling of influence of frontal sinus on NIRS signal of brain activation. In European Conference on Biomedical Optics, ECBO 2007 (Optics InfoBase Conference Papers). Optical Society of America.