Modeling of influence of frontal sinus on NIRS signal of brain activation

Daisuke Yamamoto, Shoko Kuroda, Eiji Okada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In the brain activation measurements by near infrared spectroscopy (NIRS), the partial optical path length in the brain, which is an index of the sensitivity of the NIRS signal to the brain activation, is strongly affected by the thickness and the structure of the superficial tissues. In this study, we investigate the influence of the frontal sinus on the NIRS signal of the brain activation. The light propagation in a simplified head model including a void region mimicking the frontal sinus is predicted by Monte Carlo simulation to investigate the influence of the frontal sinus on the partial optical path length in the brain and the mean optical path length in the head. The frontal sinus strongly affects the light propagation in the head. The partial optical path length for small source-detector separation tends to be increased by the presence of the frontal sinus whereas that for large source-detector separation is decreased by the influence of the frontal sinus.

Original languageEnglish
Title of host publicationDiffuse Optical Imaging of Tissue
Publication statusPublished - 2007 Nov 26
EventDiffuse Optical Imaging of Tissue - Munich, Germany
Duration: 2007 Jun 192007 Jun 21

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6629
ISSN (Print)1605-7422

Other

OtherDiffuse Optical Imaging of Tissue
CountryGermany
CityMunich
Period07/6/1907/6/21

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Keywords

  • Brain activation measurement
  • Frontal sinus
  • Near infrared spectroscopy
  • Partial optical path length

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Yamamoto, D., Kuroda, S., & Okada, E. (2007). Modeling of influence of frontal sinus on NIRS signal of brain activation. In Diffuse Optical Imaging of Tissue [66290S] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6629).