Modern management for brain metastasis patients using stereotactic radiosurgery: Literature review and the authors’ gamma knife treatment experiences

Yoshinori Higuchi, Masaaki Yamamoto, Toru Serizawa, Hitoshi Aiyama, Yasunori Sato, Bierta E. Barfod

Research output: Contribution to journalReview article

8 Citations (Scopus)


Historically, whole brain radiotherapy was administered to most patients with brain metastases. However, over the past three decades, stereotactic radiosurgery (SRS), targeted at individual cranial lesions, has been accepted widely. In this study, based on the authors’ experiences along with published data, recent trends in SRS for brain metastases are discussed. This article focuses on the following issues: 1) How many tumors can or should be treated with SRS? 2) Two-/three-staged SRS for relatively large tumors, 3) post-or preoperative SRS, and 4) repeat SRS.

Original languageEnglish
Pages (from-to)1889-1899
Number of pages11
JournalCancer Management and Research
Publication statusPublished - 2018 Jan 1
Externally publishedYes



  • Brain metastases
  • Gamma knife
  • Radiosurgery
  • Radiotherapy

ASJC Scopus subject areas

  • Oncology

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