Modic changes in the cervical spine

Morio Matsumoto, Eijiro Okada, D. Ichihara, K. Chiba, Y. Toyama, Hirokazu Fujiwara, Suketaka Momoshima, Y. Nishiwaki, T. Takahata

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

We conducted a prospective follow-up MRI study of originally asymptomatic healthy subjects to clarify the development of Modic changes in the cervical spine over a ten-year period and to identify related factors. Previously, 497 asymptomatic healthy volunteers with no history of cervical trauma or surgery underwent MRI. Of these, 223 underwent a second MRI at a mean follow-up of 11.6 years (10 to 12.7). These 223 subjects comprised 133 men and 100 women with a mean age at second MRI of 50.5 years (23 to 83). Modic changes were classified as not present and types 1 to 3. Changes in Modic types over time and relationships between Modic changes and progression of degeneration of the disc or clinical symptoms were evaluated. A total of 31 subjects (13.9%) showed Modic changes at followup: type 1 in nine, type 2 in 18, type 3 in two, and types 1 and 2 in two. Modic changes at follow-up were significantly associated with numbness or pain in the arm, but not with neck pain or shoulder stiffness. Age (≥ 40 years), gender (male), and pre-existing disc degeneration were significantly associated with newly developed Modic changes. In the cervical spine over a ten-year period, type 2 Modic changes developed most frequently. Newly developed Modic changes were significantly associated with age, gender, and pre-existing disc degeneration.

Original languageEnglish
Pages (from-to)678-683
Number of pages6
JournalJournal of Bone and Joint Surgery - Series B
Volume94 B
Issue number5
DOIs
Publication statusPublished - 2012 May

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Intervertebral Disc Degeneration
Spine
Healthy Volunteers
Hypesthesia
Neck Pain
Arm
Pain
Wounds and Injuries

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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Modic changes in the cervical spine. / Matsumoto, Morio; Okada, Eijiro; Ichihara, D.; Chiba, K.; Toyama, Y.; Fujiwara, Hirokazu; Momoshima, Suketaka; Nishiwaki, Y.; Takahata, T.

In: Journal of Bone and Joint Surgery - Series B, Vol. 94 B, No. 5, 05.2012, p. 678-683.

Research output: Contribution to journalArticle

Matsumoto, Morio ; Okada, Eijiro ; Ichihara, D. ; Chiba, K. ; Toyama, Y. ; Fujiwara, Hirokazu ; Momoshima, Suketaka ; Nishiwaki, Y. ; Takahata, T. / Modic changes in the cervical spine. In: Journal of Bone and Joint Surgery - Series B. 2012 ; Vol. 94 B, No. 5. pp. 678-683.
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