Modification of cardiac phenotype in Tbx1 hypomorphic mice

Takatoshi Tsuchihashi; Reina Ishizaki; Jun Maeda; Akimichi Shibata; Keiko Uchida; Deepak Srivastava; Hiroyuki Yamagishi

doi:10.1007/978-4-431-54628-3_28

Modification of cardiac phenotype in Tbx1 hypomorphic mice

Takatoshi Tsuchihashi, Reina Ishizaki, Jun Maeda, Akimichi Shibata, Keiko Uchida, Deepak Srivastava, Hiroyuki Yamagishi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

Congenital heart disease is still the leading cause of death within the first year of life. Our lab forces on understanding the morphology of congenital heart disease. Outflow tract anomalies, including abnormal alignment or septation, account for 30 % of all congenital heart disease. To solve the developmental problem of these defects, we are interested in the role of the second heart field (SHF) that gives rise to the outflow tract structure.

Original language	English
Title of host publication	Etiology and Morphogenesis of Congenital Heart Disease
Subtitle of host publication	From Gene Function and Cellular Interaction to Morphology
Publisher	Springer Japan
Pages	215-217
Number of pages	3
ISBN (Electronic)	9784431546283
ISBN (Print)	9784431546276
DOIs	https://doi.org/10.1007/978-4-431-54628-3_28
Publication status	Published - 2016 Jan 1

Keywords

Environmental modification
Tbx1
Truncus arteriosus

ASJC Scopus subject areas

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-4-431-54628-3_28

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abstract = "Congenital heart disease is still the leading cause of death within the first year of life. Our lab forces on understanding the morphology of congenital heart disease. Outflow tract anomalies, including abnormal alignment or septation, account for 30 % of all congenital heart disease. To solve the developmental problem of these defects, we are interested in the role of the second heart field (SHF) that gives rise to the outflow tract structure.",

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AU - Tsuchihashi, Takatoshi

AU - Ishizaki, Reina

AU - Maeda, Jun

AU - Shibata, Akimichi

AU - Uchida, Keiko

AU - Srivastava, Deepak

AU - Yamagishi, Hiroyuki

PY - 2016/1/1

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AB - Congenital heart disease is still the leading cause of death within the first year of life. Our lab forces on understanding the morphology of congenital heart disease. Outflow tract anomalies, including abnormal alignment or septation, account for 30 % of all congenital heart disease. To solve the developmental problem of these defects, we are interested in the role of the second heart field (SHF) that gives rise to the outflow tract structure.

KW - Environmental modification

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KW - Truncus arteriosus

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BT - Etiology and Morphogenesis of Congenital Heart Disease

PB - Springer Japan

ER -

Modification of cardiac phenotype in Tbx1 hypomorphic mice

Abstract

Keywords

ASJC Scopus subject areas

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