Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants

Ryo Aeba, Toshiyuki Katogi, Tadashi Omoto, Ichiro Kashima, Shiaki Kawada

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Little is known about the role of modified ultrafiltration in ameliorating the adverse effects of the cardiopulmonary bypass on pulmonary function in infants. Twenty-nine nonrandomized consecutive infants (<12 months of age) who underwent unrestrictive ventricular septal defect closure between 1995 and 1998 were included in this study. Down's syndrome was associated in 9 patients. The actual ventilator settings were highly homogeneous among all patients and each time point in the study. Fourteen infants received modified ultrafiltration after the discontinuation of cardiopulmonary bypass. Fifteen un- treated patients served as the control group. Correlates of cardiac and pulmonary functions for both groups were compared. The arterial carbon dioxide tension in the experimental group was significantly lower than in the control group from 20 to 240 min after bypass. Arterial oxygenation and pulmonary arterial pressure were similar in the 2 groups. Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. This may potentially convey a beneficial impact on hemodynamics.

Original languageEnglish
Pages (from-to)300-304
Number of pages5
JournalArtificial Organs
Volume24
Issue number4
DOIs
Publication statusPublished - 2000

Fingerprint

Ultrafiltration
Cardiopulmonary Bypass
Carbon Dioxide
Carbon dioxide
Lung
Oxygenation
Hemodynamics
Control Groups
Ventricular Heart Septal Defects
Mechanical Ventilators
Down Syndrome
Arterial Pressure
Defects

Keywords

  • Cardiopulmonary bypass
  • Pulmonary function
  • Ultrafiltration

ASJC Scopus subject areas

  • Biophysics

Cite this

Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. / Aeba, Ryo; Katogi, Toshiyuki; Omoto, Tadashi; Kashima, Ichiro; Kawada, Shiaki.

In: Artificial Organs, Vol. 24, No. 4, 2000, p. 300-304.

Research output: Contribution to journalArticle

Aeba, Ryo ; Katogi, Toshiyuki ; Omoto, Tadashi ; Kashima, Ichiro ; Kawada, Shiaki. / Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. In: Artificial Organs. 2000 ; Vol. 24, No. 4. pp. 300-304.
@article{ea912153fcde49c6a2a44ce6bf33f6b5,
title = "Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants",
abstract = "Little is known about the role of modified ultrafiltration in ameliorating the adverse effects of the cardiopulmonary bypass on pulmonary function in infants. Twenty-nine nonrandomized consecutive infants (<12 months of age) who underwent unrestrictive ventricular septal defect closure between 1995 and 1998 were included in this study. Down's syndrome was associated in 9 patients. The actual ventilator settings were highly homogeneous among all patients and each time point in the study. Fourteen infants received modified ultrafiltration after the discontinuation of cardiopulmonary bypass. Fifteen un- treated patients served as the control group. Correlates of cardiac and pulmonary functions for both groups were compared. The arterial carbon dioxide tension in the experimental group was significantly lower than in the control group from 20 to 240 min after bypass. Arterial oxygenation and pulmonary arterial pressure were similar in the 2 groups. Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. This may potentially convey a beneficial impact on hemodynamics.",
keywords = "Cardiopulmonary bypass, Pulmonary function, Ultrafiltration",
author = "Ryo Aeba and Toshiyuki Katogi and Tadashi Omoto and Ichiro Kashima and Shiaki Kawada",
year = "2000",
doi = "10.1046/j.1525-1594.2000.06487.x",
language = "English",
volume = "24",
pages = "300--304",
journal = "Artificial Organs",
issn = "0160-564X",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants

AU - Aeba, Ryo

AU - Katogi, Toshiyuki

AU - Omoto, Tadashi

AU - Kashima, Ichiro

AU - Kawada, Shiaki

PY - 2000

Y1 - 2000

N2 - Little is known about the role of modified ultrafiltration in ameliorating the adverse effects of the cardiopulmonary bypass on pulmonary function in infants. Twenty-nine nonrandomized consecutive infants (<12 months of age) who underwent unrestrictive ventricular septal defect closure between 1995 and 1998 were included in this study. Down's syndrome was associated in 9 patients. The actual ventilator settings were highly homogeneous among all patients and each time point in the study. Fourteen infants received modified ultrafiltration after the discontinuation of cardiopulmonary bypass. Fifteen un- treated patients served as the control group. Correlates of cardiac and pulmonary functions for both groups were compared. The arterial carbon dioxide tension in the experimental group was significantly lower than in the control group from 20 to 240 min after bypass. Arterial oxygenation and pulmonary arterial pressure were similar in the 2 groups. Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. This may potentially convey a beneficial impact on hemodynamics.

AB - Little is known about the role of modified ultrafiltration in ameliorating the adverse effects of the cardiopulmonary bypass on pulmonary function in infants. Twenty-nine nonrandomized consecutive infants (<12 months of age) who underwent unrestrictive ventricular septal defect closure between 1995 and 1998 were included in this study. Down's syndrome was associated in 9 patients. The actual ventilator settings were highly homogeneous among all patients and each time point in the study. Fourteen infants received modified ultrafiltration after the discontinuation of cardiopulmonary bypass. Fifteen un- treated patients served as the control group. Correlates of cardiac and pulmonary functions for both groups were compared. The arterial carbon dioxide tension in the experimental group was significantly lower than in the control group from 20 to 240 min after bypass. Arterial oxygenation and pulmonary arterial pressure were similar in the 2 groups. Modified ultrafiltration improves carbon dioxide removal after cardiopulmonary bypass in infants. This may potentially convey a beneficial impact on hemodynamics.

KW - Cardiopulmonary bypass

KW - Pulmonary function

KW - Ultrafiltration

UR - http://www.scopus.com/inward/record.url?scp=0034021402&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034021402&partnerID=8YFLogxK

U2 - 10.1046/j.1525-1594.2000.06487.x

DO - 10.1046/j.1525-1594.2000.06487.x

M3 - Article

VL - 24

SP - 300

EP - 304

JO - Artificial Organs

JF - Artificial Organs

SN - 0160-564X

IS - 4

ER -