Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation

Jun Matsumoto, Toshiyuki Fujiwara, Osamu Takahashi, Meigen Liu, Akio Kimura, Junichi Ushiba

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Background. The mu event-related desynchronization (ERD) is supposed to reflect motor preparation and appear during motor imagery. The aim of this study is to examine the modulation of ERD with transcranial direct current stimulation (tDCS). Methods. Six healthy subjects were asked to imagine their right hand grasping something after receiving a visual cue. Electroencephalograms (EEGs) were recorded near the left M1. ERD of the mu rhythm (mu ERD) by right hand motor imagery was measured. tDCS (10 min, 1 mA) was used to modulate the cortical excitability of M1. Anodal, cathodal, and sham tDCS were tested in each subject with a randomized sequence on different days. Each condition was separated from the preceding one by more than 1 week in the same subject. Before and after tDCS, mu ERD was assessed. The motor thresholds (MT) of the left M1 were also measured with transcranial magnetic stimulation. Results. Mu ERD significantly increased after anodal stimulation, whereas it significantly decreased after cathodal stimulation. There was a significant correlation between mu ERD and MT. Conclusions. Opposing effects on mu ERD based on the orientation of the stimulation suggest that mu ERD is affected by cortical excitability.

Original languageEnglish
Article number27
JournalJournal of NeuroEngineering and Rehabilitation
Volume7
Issue number1
DOIs
Publication statusPublished - 2010

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Imagery (Psychotherapy)
Hand
Transcranial Magnetic Stimulation
Cues
Electroencephalography
Healthy Volunteers
Transcranial Direct Current Stimulation
Cortical Excitability

ASJC Scopus subject areas

  • Rehabilitation
  • Health Informatics

Cite this

Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation. / Matsumoto, Jun; Fujiwara, Toshiyuki; Takahashi, Osamu; Liu, Meigen; Kimura, Akio; Ushiba, Junichi.

In: Journal of NeuroEngineering and Rehabilitation, Vol. 7, No. 1, 27, 2010.

Research output: Contribution to journalArticle

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