Molecular biology of glioma

Tomotoshi Marumoto, Hideyuki Saya

Research output: Chapter in Book/Report/Conference proceedingChapter

51 Citations (Scopus)

Abstract

Glioblastoma (GBM) is the most aggressive form of glioma. Despite ceaseless efforts by researchers and physicians to find new therapeutic strategies, there have been no significant advances in the treatment of GBMs for several decades and most patients with GBM die within one and half years of diagnosis. Undoubtedly, one reason for this is the insufficient understanding of the initiation and progression of GBMs at the molecular level. However, recent information regarding the genetic and epigenetic alterations and the microRNAs that are aberrantly activated or inactivated in GBMs has helped elucidate the formation of GBM in more detail. Here, we describe recent advances in the understanding of the biology of GBMs.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
Pages2-11
Number of pages10
Volume746
DOIs
Publication statusPublished - 2012

Publication series

NameAdvances in Experimental Medicine and Biology
Volume746
ISSN (Print)00652598

Fingerprint

Molecular biology
Glioblastoma
MicroRNAs
Glioma
Molecular Biology
Epigenomics
Research Personnel
Physicians
Therapeutics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Marumoto, T., & Saya, H. (2012). Molecular biology of glioma. In Advances in Experimental Medicine and Biology (Vol. 746, pp. 2-11). (Advances in Experimental Medicine and Biology; Vol. 746). https://doi.org/10.1007/978-1-4614-3146-6_1

Molecular biology of glioma. / Marumoto, Tomotoshi; Saya, Hideyuki.

Advances in Experimental Medicine and Biology. Vol. 746 2012. p. 2-11 (Advances in Experimental Medicine and Biology; Vol. 746).

Research output: Chapter in Book/Report/Conference proceedingChapter

Marumoto, T & Saya, H 2012, Molecular biology of glioma. in Advances in Experimental Medicine and Biology. vol. 746, Advances in Experimental Medicine and Biology, vol. 746, pp. 2-11. https://doi.org/10.1007/978-1-4614-3146-6_1
Marumoto T, Saya H. Molecular biology of glioma. In Advances in Experimental Medicine and Biology. Vol. 746. 2012. p. 2-11. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-1-4614-3146-6_1
Marumoto, Tomotoshi ; Saya, Hideyuki. / Molecular biology of glioma. Advances in Experimental Medicine and Biology. Vol. 746 2012. pp. 2-11 (Advances in Experimental Medicine and Biology).
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