The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.
|Number of pages||4|
|Journal||Cytogenetics and Cell Genetics|
|Publication status||Published - 1997 Jan 1|
ASJC Scopus subject areas
- Cell Biology