Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues

K. Uchida, A. Yoshimura, J. Inazawa, K. Yanagisawa, H. Osada, A. Masuda, T. Saito, T. Takahashi, A. Miyajima, T. Takahashi

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalCytogenetic and Genome Research
Volume78
Issue number3-4
DOIs
Publication statusPublished - 1997 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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