Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues

K. Uchida, Akihiko Yoshimura, J. Inazawa, K. Yanagisawa, H. Osada, A. Masuda, T. Saito, Takahashi Takahashi, A. Miyajima, T. Takahashi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalCytogenetics and Cell Genetics
Volume78
Issue number3-4
Publication statusPublished - 1997
Externally publishedYes

Fingerprint

Human Chromosomes
Molecular Cloning
Fetus
Fluorescence In Situ Hybridization
Northern Blotting
Genes
Epithelium
Complementary DNA
Kidney
Lung
Growth
Neoplasms
cytokine inducible SH2-containing protein

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

Cite this

Uchida, K., Yoshimura, A., Inazawa, J., Yanagisawa, K., Osada, H., Masuda, A., ... Takahashi, T. (1997). Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues. Cytogenetics and Cell Genetics, 78(3-4), 209-212.

Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues. / Uchida, K.; Yoshimura, Akihiko; Inazawa, J.; Yanagisawa, K.; Osada, H.; Masuda, A.; Saito, T.; Takahashi, Takahashi; Miyajima, A.; Takahashi, T.

In: Cytogenetics and Cell Genetics, Vol. 78, No. 3-4, 1997, p. 209-212.

Research output: Contribution to journalArticle

Uchida, K, Yoshimura, A, Inazawa, J, Yanagisawa, K, Osada, H, Masuda, A, Saito, T, Takahashi, T, Miyajima, A & Takahashi, T 1997, 'Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues', Cytogenetics and Cell Genetics, vol. 78, no. 3-4, pp. 209-212.
Uchida, K. ; Yoshimura, Akihiko ; Inazawa, J. ; Yanagisawa, K. ; Osada, H. ; Masuda, A. ; Saito, T. ; Takahashi, Takahashi ; Miyajima, A. ; Takahashi, T. / Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues. In: Cytogenetics and Cell Genetics. 1997 ; Vol. 78, No. 3-4. pp. 209-212.
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