Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues

K. Uchida; A. Yoshimura; J. Inazawa; K. Yanagisawa; H. Osada; A. Masuda; T. Saito; T. Takahashi; A. Miyajima; T. Takahashi

doi:10.1159/000134658

Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues

K. Uchida, A. Yoshimura, J. Inazawa, K. Yanagisawa, H. Osada, A. Masuda, T. Saito, T. Takahashi, A. Miyajima, T. Takahashi

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22 Citations (Scopus)

Abstract

The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.

Original language	English
Pages (from-to)	209-212
Number of pages	4
Journal	Cytogenetics and Cell Genetics
Volume	78
Issue number	3-4
DOIs	https://doi.org/10.1159/000134658
Publication status	Published - 1997 Jan 1
Externally published	Yes

ASJC Scopus subject areas

Genetics
Cell Biology

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title = "Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues",

abstract = "The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.",

author = "K. Uchida and A. Yoshimura and J. Inazawa and K. Yanagisawa and H. Osada and A. Masuda and T. Saito and T. Takahashi and A. Miyajima and T. Takahashi",

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AU - Uchida, K.

AU - Yoshimura, A.

AU - Inazawa, J.

AU - Yanagisawa, K.

AU - Osada, H.

AU - Masuda, A.

AU - Saito, T.

AU - Takahashi, T.

AU - Miyajima, A.

AU - Takahashi, T.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.

AB - The murine cytokine inducible SH2-containing (Cis) protein gene (Cish) was recently cloned and shown to have a growth inhibitory function. We have isolated cDNAs coding for its human homologue (CISH) and assigned the gene to 3p21.3 by fluorescence in situ hybridization. Northern blot analysis showed CISH expression in various epithelial tissues including lung and kidney, in which tumors frequently exhibit 3p21.3 deletions.

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Molecular cloning of CISH, chromosome assignment to 3p21.3, and analysis of expression in fetal and adult tissues

Abstract

ASJC Scopus subject areas

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