Abstract
Time-resolved measurement enables one to restrict the volume of tissue sampled by NIRS instrument. The light propagation in the real head is more complicated, especially early detected photons are affected by the presence of low scattering cerebrospinal fluid surrounding the brain. In this study, time-resolved spatial sensitivity profiles in the realistic adult and neonatal head models are predicted by Monte Carlo simulation. The geometry of the head models is based upon the MRI scan of the adult and neonatal heads. The photon propagation is predicted by the delta-scattering technique of Monte Carlo simulation. The time-resolved spatial sensitivity profiles in the adult head are strongly affected by the low scattering CSF layer while the effect of the CSF in the neonatal head model is less significant than that in the adult head model.
| Original language | English |
|---|---|
| Pages (from-to) | 383-390 |
| Number of pages | 8 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 4250 |
| DOIs | |
| Publication status | Published - 2001 |
| Event | Optical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States Duration: 2001 Jan 21 → 2001 Jan 23 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering