Monte carlo investigation of the effect of skull optical properties on optical pathlength in the brain

Eiji Okada, Minobu Saito, Michael Firbank, David T. Delpy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Appropriate modelling of light propagation in the adult head is important to deduce the partial optical pathlength for quantitative measurement of brain oxygenation using near infrared spectroscopy. It is known that the clear CSF layer significantly affects the light propagation in the brain and it is likely that the optical properties of the skull adjoining the CSF will also affect the light propagation, especially in the case of a layered (i.e. cortical/trabecular/cortical) bone. In this study a Monte Carlo simulation has been used to investigate the influence of the optical properties of the skull on the partial optical pathlength of light in the adult head. Results show that where the absorption coefficient of the trabecular bone is higher than that of outer cortical bone, the partial optical pathlength in the brain decreases and the detected light has not propagated through the trabecular bone. In this case the outer border of the intensity PMDF tends to be confined to the inner skull boundary with the CSF layer.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsD.A.M.D. Benaron, B. Chance, M. Ferrari, A. Katzir
Pages28-33
Number of pages6
Volume3194
DOIs
Publication statusPublished - 1997
EventProceedings of Photon Propagation in Tissues III - San Remo, Italy
Duration: 1997 Sep 61997 Sep 8

Other

OtherProceedings of Photon Propagation in Tissues III
CountryItaly
CitySan Remo
Period97/9/697/9/8

Fingerprint

skull
Light propagation
brain
Brain
Bone
Optical properties
bones
optical properties
propagation
Near infrared spectroscopy
Oxygenation
oxygenation
borders
absorptivity
infrared spectroscopy
simulation

Keywords

  • Heterogeneity
  • Near-infrared spectroscopy (NIRS)
  • Optical pathlength

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Okada, E., Saito, M., Firbank, M., & Delpy, D. T. (1997). Monte carlo investigation of the effect of skull optical properties on optical pathlength in the brain. In D. A. M. D. Benaron, B. Chance, M. Ferrari, & A. Katzir (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3194, pp. 28-33) https://doi.org/10.1117/12.301064

Monte carlo investigation of the effect of skull optical properties on optical pathlength in the brain. / Okada, Eiji; Saito, Minobu; Firbank, Michael; Delpy, David T.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / D.A.M.D. Benaron; B. Chance; M. Ferrari; A. Katzir. Vol. 3194 1997. p. 28-33.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Okada, E, Saito, M, Firbank, M & Delpy, DT 1997, Monte carlo investigation of the effect of skull optical properties on optical pathlength in the brain. in DAMD Benaron, B Chance, M Ferrari & A Katzir (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 3194, pp. 28-33, Proceedings of Photon Propagation in Tissues III, San Remo, Italy, 97/9/6. https://doi.org/10.1117/12.301064
Okada E, Saito M, Firbank M, Delpy DT. Monte carlo investigation of the effect of skull optical properties on optical pathlength in the brain. In Benaron DAMD, Chance B, Ferrari M, Katzir A, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3194. 1997. p. 28-33 https://doi.org/10.1117/12.301064
Okada, Eiji ; Saito, Minobu ; Firbank, Michael ; Delpy, David T. / Monte carlo investigation of the effect of skull optical properties on optical pathlength in the brain. Proceedings of SPIE - The International Society for Optical Engineering. editor / D.A.M.D. Benaron ; B. Chance ; M. Ferrari ; A. Katzir. Vol. 3194 1997. pp. 28-33
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