Monte Carlo prediction of meantime photon measurement density functions

Muneo Ono, Eiji Okada

Research output: Contribution to journalConference article


The scattering of tissue causes the ambiguity of volume of tissue interrogated by near infrared spectroscopy (NIRS) instruments. The sampling volume, which is the volume of tissue interrogated by NIRS instrument with CW light, can be predicted by calculating the distribution of light which arrives the detector. Recently, time-resolved and frequency modulated measurements has been applied to near-infrared spectroscopy (NIRS) instruments. Although the volume of tissue interrogated by the measurements of mean time, phase and so forth may be different from that by CW intensity measurement, there are very few studies on the volume of tissue interrogated by time-resolved and frequency domain measurements. In this study a Monte Carlo algorithm to predict the volume of tissue interrogated by mean time measurements is proposed and is applied to homogeneous and layered models. The volume of tissue interrogated by mean time measurement is significantly different from the sampling volume.

Original languageEnglish
Pages (from-to)20-27
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 1999 Jan 1
EventProceedings of the 1998 Photon Propagation in Tissues IV - Stockholm, SWE
Duration: 1998 Sep 91998 Sep 11


ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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