Monte Carlo simulation of characteristics of OCT signal from the boundary of optical property mismatch

Masaki Hojo, Eiji Okada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The optical coherence tomography (OCT) has been successfully applied to diagnostic imaging of transparent ocular organs. In case of highly scattering tissues such as skin and mucous membrane, and the OCT signal includes noise component due to multiple scattering in tissue, the characteristics of the OCT signal from the highly scattering tissue is more complex. In this study, we investigate the characteristics of the OCT signal from the low-scattering and highly scattering tissues by Monte Carlo simulation. In case of low-scattering tissue, the intensity of the signal is maximised when the focal depth equals the probing depth and the spurious peak of the noise due to scattering is observed at the focal depth in the OCT image. In case of highly scattering tissue, the intensity of the signal is maximised when the focal depth is smaller than the probing depth and the noise is almost independent of the focal depth.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2003
PublisherOptica Publishing Group (formerly OSA)
Pages190-197
Number of pages8
ISBN (Electronic)9781557528209
Publication statusPublished - 2003
EventEuropean Conference on Biomedical Optics, ECBO 2003 - Munich, Germany
Duration: 2003 Jun 22 → …

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2003
Country/TerritoryGermany
CityMunich
Period03/6/22 → …

Keywords

  • Optical coherence tomography
  • optical property mismatch
  • photon migration in tissue

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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