TY - JOUR
T1 - Morbidity of Tokyo-area centenarians and its relationship to functional status
AU - Takayama, Michiyo
AU - Hirose, Nobuyoshi
AU - Arai, Yasumichi
AU - Gondo, Yasuyuki
AU - Shimizu, Kenichiro
AU - Ebihara, Yoshinori
AU - Yamamura, Ken
AU - Nakazawa, Susumu
AU - Inagaki, Hiroki
AU - Masui, Yukie
AU - Kitagawa, Koji
N1 - Funding Information:
ACKNOWLEDGMENTS This work was supported by a grant for a multidisciplinary study of centenarians and its international comparison (principal investigator, Nobuyoshi Hirose) sponsored by the Ministry of Health, Labor and Welfare of the Japanese Government, and partly by a grant sponsored by the Keio Health Counseling Center, Tokyo, Japan.
PY - 2007/7
Y1 - 2007/7
N2 - Background. Research in Western countries has shown most centenarians to be survivors with multiple comorbidities. However, Japanese centenarians' morbidity and its relationship to functional status has yet to be elucidated. The aim of this study is to clarify the association of morbidity with the physical and cognitive function of centenarians. We examined Tokyo-area centenarians to determine their kinds of morbidity profiles and how such morbidity related to their functional status. Methods. We studied 302 centenarians living in Tokyo (101.2 ± 1.8 years; 65 men, 237 women), and assessed their physical status, morbidity, and use of medication. Activities of daily living and cognitive function were also assessed using the Barthel Index and the Clinical Dementia Rating. Results. More than 95% of the centenarians had chronic diseases. Both the physical and cognitive functions were significantly higher in men. The present and previous illnesses most frequently included hypertension, heart disease, stroke, fractures, and cataracts. Fractures were observed significantly more frequently in women. Diabetes mellitus was uncommon. The physical and cognitive function of centenarians with a history of stroke or fracture were particularly poor, whereas those centenarians with hypertension tended to show a high level of physical and cognitive function. Conclusions. Almost all centenarians had chronic diseases. Stroke and fracture were correlated with poorer function; therefore, we hypothesize that prevention of stroke and fracture might improve functional status in the oldest-old.
AB - Background. Research in Western countries has shown most centenarians to be survivors with multiple comorbidities. However, Japanese centenarians' morbidity and its relationship to functional status has yet to be elucidated. The aim of this study is to clarify the association of morbidity with the physical and cognitive function of centenarians. We examined Tokyo-area centenarians to determine their kinds of morbidity profiles and how such morbidity related to their functional status. Methods. We studied 302 centenarians living in Tokyo (101.2 ± 1.8 years; 65 men, 237 women), and assessed their physical status, morbidity, and use of medication. Activities of daily living and cognitive function were also assessed using the Barthel Index and the Clinical Dementia Rating. Results. More than 95% of the centenarians had chronic diseases. Both the physical and cognitive functions were significantly higher in men. The present and previous illnesses most frequently included hypertension, heart disease, stroke, fractures, and cataracts. Fractures were observed significantly more frequently in women. Diabetes mellitus was uncommon. The physical and cognitive function of centenarians with a history of stroke or fracture were particularly poor, whereas those centenarians with hypertension tended to show a high level of physical and cognitive function. Conclusions. Almost all centenarians had chronic diseases. Stroke and fracture were correlated with poorer function; therefore, we hypothesize that prevention of stroke and fracture might improve functional status in the oldest-old.
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U2 - 10.1093/gerona/62.7.774
DO - 10.1093/gerona/62.7.774
M3 - Article
C2 - 17634326
AN - SCOPUS:34548425592
VL - 62
SP - 774
EP - 782
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
SN - 1079-5006
IS - 7
ER -