Motor-related intracortical steal phenomenon detected by multichannel functional near-infrared spectroscopy imaging

Takenori Akiyama, Takayuki Oohira, Toshinori Kato, Yasuo Toda, Maaya Orii, Kenji Hiraga, Atsushi Fukunaga, Masahito Kobayashi, Satoshi Onozuka, Takeshi Kawase

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Patients with severe cerebral ischemia may lose autoregulation to increase cerebral blood flow following neural activity. Although the steal phenomenon under conventional cerebral blood flow study has been known as a high-risk factor for stroke, the cerebral oxygen hemodynamics in ischemic patients during functional activation has not been thoroughly investigated. In this study, we present rare cases with intracortical steal phenomenon during motor tasks detected by multichannel functional near-infrared spectroscopy before and after surgery. Methods: The relative concentration change of oxygenated, deoxygenated and total hemoglobin in and around the primary sensorimotor cortex during contralateral hand grasping was investigated in 11 patients with severe internal carotid artery stenosis. Results: In 3 patients, the concentration of total hemoglobin around the primary sensorimotor cortex significantly decreased in response to motor stimulation and returned to baseline soon after termination of the motor task. This phenomenon partially disappeared postoperatively in all patients who underwent surgery. The remaining 8 patients showed no signs of total hemoglobin decrease in and around the sensorimotor cortex. In 9 patients, lack of decrease in deoxygenated hemoglobin in the center of the primary motor cortex during the motor task was observed and 3 of them showed significant increase in deoxygenated hemoglobin. Conclusions: We have demonstrated that in some patients with severe ischemia, an abnormal motor-related steal phenomenon can be observed. This phenomenon can be modulated by surgical intervention and might imply the severity of ischemia.

Original languageEnglish
Pages (from-to)337-346
Number of pages10
JournalCerebrovascular Diseases
Volume20
Issue number5
DOIs
Publication statusPublished - 2005 Oct

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Near-Infrared Spectroscopy
Hemoglobins
Cerebrovascular Circulation
Ischemia
Carotid Stenosis
Motor Cortex
Brain Ischemia
Homeostasis
Hand
Hemodynamics
Stroke
Oxygen

Keywords

  • Internal carotid artery stenosis
  • Ischemia
  • Near-infrared spectroscopy
  • Steal phenomenon

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Motor-related intracortical steal phenomenon detected by multichannel functional near-infrared spectroscopy imaging. / Akiyama, Takenori; Oohira, Takayuki; Kato, Toshinori; Toda, Yasuo; Orii, Maaya; Hiraga, Kenji; Fukunaga, Atsushi; Kobayashi, Masahito; Onozuka, Satoshi; Kawase, Takeshi.

In: Cerebrovascular Diseases, Vol. 20, No. 5, 10.2005, p. 337-346.

Research output: Contribution to journalArticle

Akiyama, T, Oohira, T, Kato, T, Toda, Y, Orii, M, Hiraga, K, Fukunaga, A, Kobayashi, M, Onozuka, S & Kawase, T 2005, 'Motor-related intracortical steal phenomenon detected by multichannel functional near-infrared spectroscopy imaging', Cerebrovascular Diseases, vol. 20, no. 5, pp. 337-346. https://doi.org/10.1159/000087934
Akiyama, Takenori ; Oohira, Takayuki ; Kato, Toshinori ; Toda, Yasuo ; Orii, Maaya ; Hiraga, Kenji ; Fukunaga, Atsushi ; Kobayashi, Masahito ; Onozuka, Satoshi ; Kawase, Takeshi. / Motor-related intracortical steal phenomenon detected by multichannel functional near-infrared spectroscopy imaging. In: Cerebrovascular Diseases. 2005 ; Vol. 20, No. 5. pp. 337-346.
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