MR appearance and spectral features of injected ethanol in the liver: Implication for fast MR-guided percutaneous ethanol injection therapy

Hiroshi Shinmoto; Robert V. Mulkern; Koichi Oshio; Stuart G. Silverman; Vincent M. Colucci; Ferenc A. Jolesz

doi:10.1097/00004728-199701000-00015

MR appearance and spectral features of injected ethanol in the liver: Implication for fast MR-guided percutaneous ethanol injection therapy

Hiroshi Shinmoto, Robert V. Mulkern, Koichi Oshio, Stuart G. Silverman, Vincent M. Colucci, Ferenc A. Jolesz

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Purpose: Our goal was to evaluate several fast MR strategies for monitoring ethanol distributions so that percutaneous ethanol injection might be guided with MRI. Method: Fast RF spoiled GRE sequences (SPGR) and T2- weighted rapid acquisition with relaxation enhancement (RARE) sequences with and without spectroscopic-quality water suppression techniques were assessed for their ability to depict the distribution of injected ethanol in ex vivo pig liver. A line scan Carr-Purcell-Meiboom-Gill spectroscopic imaging sequence was used to validate observations and measure spectral relaxation characteristics of the ethanol signal in liver. Injected deuterated ethanol was also tested as an alternative possibility to depict the distribution of ethanol. Results: The water-suppressed T2-weighted RARE sequence depicted the distribution of ethanol better than other sequences. Deuterated ethanol appeared as a signal void on all sequences. Conclusion: Water-suppressed T2- weighted RARE sequences could be useful to rapidly monitor MR-guided PEI.

Original language	English
Pages (from-to)	82-88
Number of pages	7
Journal	Journal of Computer Assisted Tomography
Volume	21
Issue number	1
DOIs	https://doi.org/10.1097/00004728-199701000-00015
Publication status	Published - 1997
Externally published	Yes

Keywords

Ethanol
Liver, neoplasms
Magnetic resonance imaging
Magnetic resonance imaging, techniques
spectroscopy (MRS)

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/00004728-199701000-00015

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title = "MR appearance and spectral features of injected ethanol in the liver: Implication for fast MR-guided percutaneous ethanol injection therapy",

abstract = "Purpose: Our goal was to evaluate several fast MR strategies for monitoring ethanol distributions so that percutaneous ethanol injection might be guided with MRI. Method: Fast RF spoiled GRE sequences (SPGR) and T2- weighted rapid acquisition with relaxation enhancement (RARE) sequences with and without spectroscopic-quality water suppression techniques were assessed for their ability to depict the distribution of injected ethanol in ex vivo pig liver. A line scan Carr-Purcell-Meiboom-Gill spectroscopic imaging sequence was used to validate observations and measure spectral relaxation characteristics of the ethanol signal in liver. Injected deuterated ethanol was also tested as an alternative possibility to depict the distribution of ethanol. Results: The water-suppressed T2-weighted RARE sequence depicted the distribution of ethanol better than other sequences. Deuterated ethanol appeared as a signal void on all sequences. Conclusion: Water-suppressed T2- weighted RARE sequences could be useful to rapidly monitor MR-guided PEI.",

keywords = "Ethanol, Liver, neoplasms, Magnetic resonance imaging, Magnetic resonance imaging, techniques, spectroscopy (MRS)",

author = "Hiroshi Shinmoto and Mulkern, {Robert V.} and Koichi Oshio and Silverman, {Stuart G.} and Colucci, {Vincent M.} and Jolesz, {Ferenc A.}",

year = "1997",

doi = "10.1097/00004728-199701000-00015",

language = "English",

volume = "21",

pages = "82--88",

journal = "Journal of Computer Assisted Tomography",

issn = "0363-8715",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - MR appearance and spectral features of injected ethanol in the liver

T2 - Implication for fast MR-guided percutaneous ethanol injection therapy

AU - Shinmoto, Hiroshi

AU - Mulkern, Robert V.

AU - Oshio, Koichi

AU - Silverman, Stuart G.

AU - Colucci, Vincent M.

AU - Jolesz, Ferenc A.

PY - 1997

Y1 - 1997

N2 - Purpose: Our goal was to evaluate several fast MR strategies for monitoring ethanol distributions so that percutaneous ethanol injection might be guided with MRI. Method: Fast RF spoiled GRE sequences (SPGR) and T2- weighted rapid acquisition with relaxation enhancement (RARE) sequences with and without spectroscopic-quality water suppression techniques were assessed for their ability to depict the distribution of injected ethanol in ex vivo pig liver. A line scan Carr-Purcell-Meiboom-Gill spectroscopic imaging sequence was used to validate observations and measure spectral relaxation characteristics of the ethanol signal in liver. Injected deuterated ethanol was also tested as an alternative possibility to depict the distribution of ethanol. Results: The water-suppressed T2-weighted RARE sequence depicted the distribution of ethanol better than other sequences. Deuterated ethanol appeared as a signal void on all sequences. Conclusion: Water-suppressed T2- weighted RARE sequences could be useful to rapidly monitor MR-guided PEI.

AB - Purpose: Our goal was to evaluate several fast MR strategies for monitoring ethanol distributions so that percutaneous ethanol injection might be guided with MRI. Method: Fast RF spoiled GRE sequences (SPGR) and T2- weighted rapid acquisition with relaxation enhancement (RARE) sequences with and without spectroscopic-quality water suppression techniques were assessed for their ability to depict the distribution of injected ethanol in ex vivo pig liver. A line scan Carr-Purcell-Meiboom-Gill spectroscopic imaging sequence was used to validate observations and measure spectral relaxation characteristics of the ethanol signal in liver. Injected deuterated ethanol was also tested as an alternative possibility to depict the distribution of ethanol. Results: The water-suppressed T2-weighted RARE sequence depicted the distribution of ethanol better than other sequences. Deuterated ethanol appeared as a signal void on all sequences. Conclusion: Water-suppressed T2- weighted RARE sequences could be useful to rapidly monitor MR-guided PEI.

KW - Ethanol

KW - Liver, neoplasms

KW - Magnetic resonance imaging

KW - Magnetic resonance imaging, techniques

KW - spectroscopy (MRS)

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AN - SCOPUS:0031038472

SN - 0363-8715

VL - 21

SP - 82

EP - 88

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

IS - 1

ER -

MR appearance and spectral features of injected ethanol in the liver: Implication for fast MR-guided percutaneous ethanol injection therapy

Abstract

Keywords

ASJC Scopus subject areas

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