Multi-scale stress analysis of trabecular bone considering trabeculae morphology and biological apatite crystallite orientation

Mitsuhiro Kawagai, Naoki Takano, Takayoshi Nakano, Mitsuteru Asai

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This paper presents the multi-scale stress analysis of trabecular bone by the homogenization method bridging nano-micro-macro scales. Three-dimensional microstructure of trabeculae is obtained by the X-ray CT and the image-based modeling technique. Biological apatite (BAp) crystallite orientation is considered in the microstructure model by means of the anisotropic mechanical properties. The c-axis of BAp is set up as the maximum principal stress direction under the long term macroscopic stress condition. These properties are automatically assigned to each voxel element. To determine appropriately the microstructure model, the trabeculae morphology is analyzed and quantified as the trabecular density distribution. The proposed method is applied to pig's femur. It was revealed by the morphology analysis and homogenized macroscopic properties that the trabecular bone has plate-like characteristics. The predicted anisotropic level of the macroscopic properties was quantitatively coincident with the measured value by the X-ray diffraction analysis.

Original languageEnglish
Pages (from-to)874-880
Number of pages7
JournalZairyo/Journal of the Society of Materials Science, Japan
Volume55
Issue number9
DOIs
Publication statusPublished - 2006 Sep
Externally publishedYes

Fingerprint

Apatites
stress analysis
Apatite
apatites
Stress analysis
bones
Bone
microstructure
Microstructure
Homogenization method
femur
swine
homogenizing
X ray diffraction analysis
Macros
density distribution
x rays
mechanical properties
X rays
Mechanical properties

Keywords

  • Anisotropy
  • Biological apatite
  • Homogenization method
  • Morphology analysis
  • Multi-scale analysis
  • Trabecular bone

ASJC Scopus subject areas

  • Metals and Alloys
  • Chemical Engineering (miscellaneous)
  • Polymers and Plastics

Cite this

Multi-scale stress analysis of trabecular bone considering trabeculae morphology and biological apatite crystallite orientation. / Kawagai, Mitsuhiro; Takano, Naoki; Nakano, Takayoshi; Asai, Mitsuteru.

In: Zairyo/Journal of the Society of Materials Science, Japan, Vol. 55, No. 9, 09.2006, p. 874-880.

Research output: Contribution to journalArticle

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