Multiple cardiovascular diseases or risk factors increase the severity of Coronavirus disease 2019

Tomoyuki Yamada, Taku Ogawa, Kenta Minami, Yusuke Kusaka, Masaaki Hoshiga, Akira Ukimura, Takahide Sano, Takeshi Kitai, Taishi Yonetsu, Sho Torii, Shun Kohsaka, Shunsuke Kuroda, Koichi Node, Yuya Matsue, Shingo Matsumoto

Research output: Contribution to journalReview articlepeer-review

Abstract

Background: This study aimed to determine whether disease severity varied according to whether coronavirus disease 2019 (COVID-19) patients had multiple or single cardiovascular diseases and risk factors (CVDRFs). Methods and Results: COVID-19 patients with single (n=281) or multiple (n=412) CVDRFs were included retrospectively. Multivariable logistic regression showed no significant difference in the risk of in-hospital death between groups, but patients with multiple CVDRFs had a significantly higher risk of acute respiratory distress syndrome (odds ratio: 1.75, 95% confidence interval: 1.09-2.81). Conclusions: COVID-19 patients with multiple CVDRFs have a higher risk of complications than those with a single CDVRF.

Original languageEnglish
Pages (from-to)2111-2115
Number of pages5
JournalCirculation Journal
Volume85
Issue number11
DOIs
Publication statusPublished - 2021

Keywords

  • Cardiovascular disease
  • Cardiovascular risk factors
  • Coronavirus disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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