Multistep mixing, reaction and detection system in an extended-nano fluidic network

Yo Tanaka; Hong Trang Ngo; Yutaka Kazoe; Hisashi Shimizu; Kazuma Mawatari; Takehiko Kitamori

Multistep mixing, reaction and detection system in an extended-nano fluidic network

Yo Tanaka, Hong Trang Ngo, Yutaka Kazoe, Hisashi Shimizu, Kazuma Mawatari, Takehiko Kitamori

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this report, we developed an extended-nano (10-1000 nm) fluidic network to realize continuous flow chemical processing (CFCP) for single cell secretion analysis. Firstly, equivalent mixing was demonstrated in the network by optimizing fabrication conditions and applied pressure. Secondly, chemical reaction was realized in the network, and the products were detected by differential interference contrast thermal lens microscope (DIC-TLM). This is the smallest reaction channel network, and will be applied for single cell activity analysis.

Original language	English
Title of host publication	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages	380-382
Number of pages	3
Publication status	Published - 2011 Dec 1
Externally published	Yes
Event	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States Duration: 2011 Oct 2 → 2011 Oct 6

Publication series

Name	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume	1

Other

Other	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Country/Territory	United States
City	Seattle, WA
Period	11/10/2 → 11/10/6

Keywords

Continuous flow chemical processing (CFCP)
Extended-nano channel
Thermal lens microscope (TLM)

ASJC Scopus subject areas

Control and Systems Engineering

Cite this

Tanaka, Y., Ngo, H. T., Kazoe, Y., Shimizu, H., Mawatari, K., & Kitamori, T. (2011). Multistep mixing, reaction and detection system in an extended-nano fluidic network. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 (pp. 380-382). (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; Vol. 1).

Multistep mixing, reaction and detection system in an extended-nano fluidic network. / Tanaka, Yo; Ngo, Hong Trang; Kazoe, Yutaka; Shimizu, Hisashi; Mawatari, Kazuma; Kitamori, Takehiko.

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. p. 380-382 (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Tanaka, Y, Ngo, HT, Kazoe, Y, Shimizu, H, Mawatari, K & Kitamori, T 2011, Multistep mixing, reaction and detection system in an extended-nano fluidic network. in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, vol. 1, pp. 380-382, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, Seattle, WA, United States, 11/10/2.

Tanaka Y, Ngo HT, Kazoe Y, Shimizu H, Mawatari K, Kitamori T. Multistep mixing, reaction and detection system in an extended-nano fluidic network. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. p. 380-382. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011).

Tanaka, Yo ; Ngo, Hong Trang ; Kazoe, Yutaka ; Shimizu, Hisashi ; Mawatari, Kazuma ; Kitamori, Takehiko. / Multistep mixing, reaction and detection system in an extended-nano fluidic network. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. pp. 380-382 (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011).

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abstract = "In this report, we developed an extended-nano (10-1000 nm) fluidic network to realize continuous flow chemical processing (CFCP) for single cell secretion analysis. Firstly, equivalent mixing was demonstrated in the network by optimizing fabrication conditions and applied pressure. Secondly, chemical reaction was realized in the network, and the products were detected by differential interference contrast thermal lens microscope (DIC-TLM). This is the smallest reaction channel network, and will be applied for single cell activity analysis.",

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author = "Yo Tanaka and Ngo, {Hong Trang} and Yutaka Kazoe and Hisashi Shimizu and Kazuma Mawatari and Takehiko Kitamori",

year = "2011",

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AU - Mawatari, Kazuma

AU - Kitamori, Takehiko

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AB - In this report, we developed an extended-nano (10-1000 nm) fluidic network to realize continuous flow chemical processing (CFCP) for single cell secretion analysis. Firstly, equivalent mixing was demonstrated in the network by optimizing fabrication conditions and applied pressure. Secondly, chemical reaction was realized in the network, and the products were detected by differential interference contrast thermal lens microscope (DIC-TLM). This is the smallest reaction channel network, and will be applied for single cell activity analysis.

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KW - Thermal lens microscope (TLM)

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Multistep mixing, reaction and detection system in an extended-nano fluidic network

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