Musashi1 antigen expression in human fetal germinal matrix development

Charles Chan; Brian E. Moore; Carl W. Cotman; Hideyuki Okano; Rosemarie Tavares; Virginia Hovanesian; Halit Pinar; Conrad E. Johanson; Clive N. Svendsen; Edward G. Stopa

doi:10.1016/j.expneurol.2006.04.023

Musashi1 antigen expression in human fetal germinal matrix development

Charles Chan, Brian E. Moore, Carl W. Cotman, Hideyuki Okano, Rosemarie Tavares, Virginia Hovanesian, Halit Pinar, Conrad E. Johanson, Clive N. Svendsen, Edward G. Stopa

Department of Physiology

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Musashi1 is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashi1 in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal matrix. Our results indicate that Musashi1 is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells.

Original language	English
Pages (from-to)	515-518
Number of pages	4
Journal	Experimental Neurology
Volume	201
Issue number	2
DOIs	https://doi.org/10.1016/j.expneurol.2006.04.023
Publication status	Published - 2006 Oct

Keywords

GFAP
Germinal matrix
Ki-67
Musashi1
Nestin
Neural progenitor cell
Subventricular zone

ASJC Scopus subject areas

Neurology
Developmental Neuroscience

Access to Document

10.1016/j.expneurol.2006.04.023

Cite this

@article{3b6c9b00e8db4df5992fe7abf819d9f0,

title = "Musashi1 antigen expression in human fetal germinal matrix development",

abstract = "Musashi1 is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashi1 in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal matrix. Our results indicate that Musashi1 is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells.",

keywords = "GFAP, Germinal matrix, Ki-67, Musashi1, Nestin, Neural progenitor cell, Subventricular zone",

author = "Charles Chan and Moore, {Brian E.} and Cotman, {Carl W.} and Hideyuki Okano and Rosemarie Tavares and Virginia Hovanesian and Halit Pinar and Johanson, {Conrad E.} and Svendsen, {Clive N.} and Stopa, {Edward G.}",

note = "Funding Information: This study was supported in part by grants RR-00-003 and NIH NS27601.",

year = "2006",

month = oct,

doi = "10.1016/j.expneurol.2006.04.023",

language = "English",

volume = "201",

pages = "515--518",

journal = "Neurodegeneration",

issn = "0014-4886",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - Musashi1 antigen expression in human fetal germinal matrix development

AU - Chan, Charles

AU - Moore, Brian E.

AU - Cotman, Carl W.

AU - Okano, Hideyuki

AU - Tavares, Rosemarie

AU - Hovanesian, Virginia

AU - Pinar, Halit

AU - Johanson, Conrad E.

AU - Svendsen, Clive N.

AU - Stopa, Edward G.

N1 - Funding Information: This study was supported in part by grants RR-00-003 and NIH NS27601.

PY - 2006/10

Y1 - 2006/10

N2 - Musashi1 is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashi1 in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal matrix. Our results indicate that Musashi1 is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells.

AB - Musashi1 is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashi1 in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal matrix. Our results indicate that Musashi1 is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells.

KW - GFAP

KW - Germinal matrix

KW - Ki-67

KW - Musashi1

KW - Nestin

KW - Neural progenitor cell

KW - Subventricular zone

UR - http://www.scopus.com/inward/record.url?scp=33748415309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748415309&partnerID=8YFLogxK

U2 - 10.1016/j.expneurol.2006.04.023

DO - 10.1016/j.expneurol.2006.04.023

M3 - Article

C2 - 16777095

AN - SCOPUS:33748415309

SN - 0014-4886

VL - 201

SP - 515

EP - 518

JO - Neurodegeneration

JF - Neurodegeneration

IS - 2

ER -

Musashi1 antigen expression in human fetal germinal matrix development

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this