Musashi1 antigen expression in human fetal germinal matrix development

Charles Chan, Brian E. Moore, Carl W. Cotman, Hideyuki Okano, Rosemarie Tavares, Virginia Hovanesian, Halit Pinar, Conrad E. Johanson, Clive N. Svendsen, Edward G. Stopa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Musashi1 is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashi1 in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal matrix. Our results indicate that Musashi1 is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells.

Original languageEnglish
Pages (from-to)515-518
Number of pages4
JournalExperimental Neurology
Volume201
Issue number2
DOIs
Publication statusPublished - 2006 Oct 1

Keywords

  • GFAP
  • Germinal matrix
  • Ki-67
  • Musashi1
  • Nestin
  • Neural progenitor cell
  • Subventricular zone

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience

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