Muscle reorganization following incomplete cervical spinal cord injury in rats

Masaya Nakamura, Y. Fujimura, Y. Yato, M. Watanabe

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

This study on rats was designed to evaluate the change of biceps muscle fibers by enzyme histochemical examination and the change of distribution of motoneurons innervating biceps muscle fibers by retrograde tracer examination after incomplete spinal cord injury. Incomplete spinal cord injury was produced by placing a 20 g weight on exposed dura at the C6 level. The number of the labeled motoneurons of C6 segment significantly decreased compared with that in the control, but there were no significant changes in the other segments at 4 weeks after the injury. Moreover, there was type grouping of biceps muscle fibers at 4 weeks after the injury. These findings indicated that the incomplete cervical spinal cord injury at C6 level in rats caused the partial denervation and then reinnervation of biceps muscle fibers by the collateral sprouting of the remaining motoneurons which belonged to the same motoneuron pool of the injured motoneurons.

Original languageEnglish
Pages (from-to)752-756
Number of pages5
JournalSpinal Cord
Volume35
Issue number11
Publication statusPublished - 1997

Fingerprint

Motor Neurons
Spinal Cord Injuries
Muscles
Wounds and Injuries
Denervation
Cervical Cord
Weights and Measures
Enzymes

Keywords

  • Incomplete cervical spinal cord injury
  • Motoneuron
  • Muscle fiber type grouping
  • Partial denervation

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Nakamura, M., Fujimura, Y., Yato, Y., & Watanabe, M. (1997). Muscle reorganization following incomplete cervical spinal cord injury in rats. Spinal Cord, 35(11), 752-756.

Muscle reorganization following incomplete cervical spinal cord injury in rats. / Nakamura, Masaya; Fujimura, Y.; Yato, Y.; Watanabe, M.

In: Spinal Cord, Vol. 35, No. 11, 1997, p. 752-756.

Research output: Contribution to journalArticle

Nakamura, M, Fujimura, Y, Yato, Y & Watanabe, M 1997, 'Muscle reorganization following incomplete cervical spinal cord injury in rats', Spinal Cord, vol. 35, no. 11, pp. 752-756.
Nakamura, Masaya ; Fujimura, Y. ; Yato, Y. ; Watanabe, M. / Muscle reorganization following incomplete cervical spinal cord injury in rats. In: Spinal Cord. 1997 ; Vol. 35, No. 11. pp. 752-756.
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