Mycetoindole, an N-acyl dehydrotryptophan with plant growth inhibitory activity from an actinomycete of the genus Actinomycetospora

Shun Saito, Naoya Oku, Yasuhiro Igarashi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A rare actinomycetal strain of the genus Actinomycetospora was found to produce a new tryptophan derivative, designated mycetoindole (1). The structure of 1 was determined to be N-3-methylcrotonoyl (Z)-dehydrotryptophan by NMR and MS analytical methods. Compound 1 reduced the root growth of lettuce Lactuca sativa seedlings at concentrations above 0.1 μM and almost completely inhibited seed germination at 10 μM.

Original languageEnglish
Pages (from-to)44-47
Number of pages4
JournalJournal of Antibiotics
Volume75
Issue number1
DOIs
Publication statusPublished - 2022 Jan

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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