Myofibroblasts in fibrous tumors and fibrosis in various organs

I. Nakanishi, K. Kajikawa, Y. Okada, K. Eguchi

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The morphology and population of myofibroblasts detected by electron microscopy in fibrous tumors and fibrosis in various organs have been examined. The myofibroblast was identified by characteristic features of the indented nucleus, bundles of abundant microfilaments with dense bodies, focal basal lamina and well-developed rough endoplasmic reticulum. It has been observed that myofibroblasts in a variety of fibrous tumors and fibrosis appeared predominantly in fibromatosis and reparative process of deep fibrous tissues and organs particularly in the lesions involving the fascia and subcutaneous tissue. It was suggested that myofibroblasts would be modified fibroblasts to which fibroblasts in the fascia and deeply situated fibrous tissue transformed during proliferation and differentiation.

Original languageEnglish
Pages (from-to)423-437
Number of pages15
JournalActa Pathologica Japonica
Volume31
Issue number3
Publication statusPublished - 1981

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Myofibroblasts
Fibrosis
Fascia
Neoplasms
Fibroblasts
Fibroma
Rough Endoplasmic Reticulum
Subcutaneous Tissue
Actin Cytoskeleton
Basement Membrane
Electron Microscopy
Population

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Nakanishi, I., Kajikawa, K., Okada, Y., & Eguchi, K. (1981). Myofibroblasts in fibrous tumors and fibrosis in various organs. Acta Pathologica Japonica, 31(3), 423-437.

Myofibroblasts in fibrous tumors and fibrosis in various organs. / Nakanishi, I.; Kajikawa, K.; Okada, Y.; Eguchi, K.

In: Acta Pathologica Japonica, Vol. 31, No. 3, 1981, p. 423-437.

Research output: Contribution to journalArticle

Nakanishi, I, Kajikawa, K, Okada, Y & Eguchi, K 1981, 'Myofibroblasts in fibrous tumors and fibrosis in various organs', Acta Pathologica Japonica, vol. 31, no. 3, pp. 423-437.
Nakanishi I, Kajikawa K, Okada Y, Eguchi K. Myofibroblasts in fibrous tumors and fibrosis in various organs. Acta Pathologica Japonica. 1981;31(3):423-437.
Nakanishi, I. ; Kajikawa, K. ; Okada, Y. ; Eguchi, K. / Myofibroblasts in fibrous tumors and fibrosis in various organs. In: Acta Pathologica Japonica. 1981 ; Vol. 31, No. 3. pp. 423-437.
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