Myositis and interstitial lung disease associated with autoantibody to a transfer RNA-related protein Wa

M. Kajihara, M. Kuwana, H. Tokuda, K. Yamane, M. Kubo, M. Hirakata, T. Mimori

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

We describe 2 patients with myositis and interstitial lung disease with the autoantibody to Wa antigen, a 48-kDa transfer RNA-related protein. In contrast to the previous description of anti-Wa antibody, our patients lacked systemic sclerosis-related features, but had clinical features consistent with those associated with antibodies to aminoacyl-transfer RNA synthetases. The difference in clinical presentation between our patients and patients with systemic sclerosis may be explained by recognition of different epitopes on the Wa antigen.

Original languageEnglish
Pages (from-to)2707-2710
Number of pages4
JournalJournal of Rheumatology
Volume27
Issue number11
Publication statusPublished - 2000

Keywords

  • Autoantibody
  • Interstitial lung disease
  • Polymyositis
  • Transfer RNA

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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