Narrow-band imaging in the diagnosis of colorectal mucosal lesions: A pilot study

H. Machida, Y. Sano, Y. Hamamoto, M. Muto, T. Kozu, H. Tajiri, S. Yoshida

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Abstract

Background and Study Aims: A newly developed narrow-band imaging (NBI) technique, in which modified optical filters were used in the light source of a video endoscope system, was applied during colonoscopy in a clinical setting. This pilot study evaluated the clinical feasibility of the NBI system for evaluating colorectal lesions. Patients and Methods: A total of 43 colorectal lesions in 34 patients were included in the study. The quality of visualization of colorectal lesions and the accuracy of differentiation between neoplastic and non-neoplastic lesions using the NBI system were evaluated in comparison with results from conventional colonoscopy and with chromoendoscopy. Results: For pit pattern delineation, NBI was superior to conventional endoscopy (P < 0.001 ), but inferior to chromoendoscopy (P < 0.05. NBI achieved better visualization of the mucosal vascular network and of the hue of lesions than conventional endoscopy (P < 0.05). However there was no significant difference between NBI and chromoendoscopy in differentiating neoplastic from non-neoplastic lesions (both techniques had a sensitivity of 100% and a specificity 75%). This was better than the results of conventional colonoscopy (sensitivity 83%, specificity 44%; P < 0.05 for specificity). Conclusions: These results suggest that in the examination of colonic lesions the NBI system provides imaging features additional to those of both conventional endoscopy and chromoendoscopy. For distinguishing neoplasms from non-neoplastic lesions, NBI was equivalent to chromoendoscopy.

Original languageEnglish
Pages (from-to)1094-1098
Number of pages5
JournalEndoscopy
Volume36
Issue number12
DOIs
Publication statusPublished - 2004 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology

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    Machida, H., Sano, Y., Hamamoto, Y., Muto, M., Kozu, T., Tajiri, H., & Yoshida, S. (2004). Narrow-band imaging in the diagnosis of colorectal mucosal lesions: A pilot study. Endoscopy, 36(12), 1094-1098. https://doi.org/10.1055/s-2004-826040