Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010: General view of the pathogens' antibacterial susceptibility

Katsunori Yanagihara, Junichi Kadota, Nobuki Aoki, Tetsuya Matsumoto, Masaki Yoshida, Morimasa Yagisawa, Toyoko Oguri, Junko Sato, Kazuhiko Ogasawara, Tomotaro Wakamura, Keisuke Sunakawa, Akira Watanabe, Satoshi Iwata, Mitsuo Kaku, Hideaki Hanaki, Yoshinobu Ohsaki, Tomohisa Watari, Eri Toyoshima, Kenichi Takeuchi, Mayumi ShiokoshiHiroaki Takeda, Makoto Miki, Toshio Kumagai, Susumu Nakanowatari, Hiroshi Takahashi, Mutsuko Utagawa, Hajime Nishiya, Sayoko Kawakami, Nobuyuki Kobayashi, Jin Takasaki, Kazuhisa Mezaki, Hisami Konosaki, Yasuko Aoki, Yumiko Yamamoto, Michi Shoji, Hajime Goto, Takeshi Saraya, Daisuke Kurai, Mitsuhiro Okazaki, Yoshihito Niki, Koichiro Yoshida, Akihiko Kawana, Katsu Saionji, Yuji Fujikura, Naoki Miyazawa, Makoto Kudo, Yoshimi Sato, Masaki Yamamoto, Takashi Yoshida, Masahiko Nakamura, Hiroki Tsukada, Yumiko Imai, Ayami Tsukada, Satoshi Kawasaki, Yasuo Honma, Toshinobu Yamamoto, Nobuyoshi Ban, Hiroshige Mikamo, Haruki Sawamura, Takayuki Miyara, Hirofumi Toda, Kaori Sato, Tadahiro Nakamura, Yasunori Fujikawa, Noriko Mitsuno, Keiichi Mikasa, Kei Kasahara, Reiko Sano, Keisuke Sugimoto, Seishi Asari, Isao Nishi, Masahiro Toyokawa, Naoyuki Miyashita, Yutaka Koguchi, Nobuchika Kusano, Eiichirou Mihara, Masao Kuwabara, Yaeko Watanabe, Yuji Kawasaki, Kenichi Takeda, Hirokazu Tokuyasu, Kayoko Masui, Kiyoshi Negayama, Kazufumi Hiramatsu, Yosuke Aoki, Mami Fukuoka, Hiroki Magarifuchi, Zenzo Nagasawa, Moritaka Suga, Hiroyuki Muranaka, Yoshitomo Morinaga, Junichi Honda, Masaki Fujita

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, was conducted by Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for Clinical Microbiology in 2010.The isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period from January and April 2010 by three societies. Antimicrobial susceptibility testing was conducted at the central reference laboratory according to the method recommended by Clinical and Laboratory Standard Institutes using maximum 45 antibacterial agents.Susceptibility testing was evaluable with 954 strains (206 Staphylococcus aureus, 189 Streptococcus pneumoniae, 4 Streptococcus pyogenes, 182 Haemophilus influenzae, 74 Moraxella catarrhalis, 139 Klebsiella pneumoniae and 160 Pseudomonas aeruginosa). Ratio of methicillin-resistant S.aureus was as high as 50.5%, and those of penicillin-intermediate and -resistant S.pneumoniae were 1.1% and 0.0%, respectively. Among H.influenzae, 17.6% of them were found to be β-lactamase-non-producing ampicillin (ABPC)-intermediately resistant, 33.5% to be β-lactamase-non-producing ABPC-resistant and 11.0% to be β-lactamase-producing ABPC-resistant strains. Extended spectrum β-lactamase-producing K.pneumoniae and multi-drug resistant P.aeruginosa with metallo β-lactamase were 2.9% and 0.6%, respectively.Continuous national surveillance of antimicrobial susceptibility of respiratory pathogens is crucial in order to monitor changing patterns of susceptibility and to be able to update treatment recommendations on a regular basis.

Original languageEnglish
Pages (from-to)410-420
Number of pages11
JournalJournal of Infection and Chemotherapy
Volume21
Issue number6
DOIs
Publication statusPublished - 2015 Jun 1
Externally publishedYes

Fingerprint

Microbiology
Communicable Diseases
Pneumonia
Moraxella (Branhamella) catarrhalis
Drug Therapy
Methicillin Resistance
Streptococcus pyogenes
Haemophilus influenzae
Klebsiella pneumoniae
Ampicillin
Streptococcus pneumoniae
Respiratory Tract Infections
Penicillins
Pseudomonas aeruginosa
Human Influenza
Staphylococcus aureus
Japan
Anti-Bacterial Agents
Pharmaceutical Preparations
Therapeutics

Keywords

  • Resistance
  • Respiratory tract infection
  • Surveillance
  • Susceptibility

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010 : General view of the pathogens' antibacterial susceptibility. / Yanagihara, Katsunori; Kadota, Junichi; Aoki, Nobuki; Matsumoto, Tetsuya; Yoshida, Masaki; Yagisawa, Morimasa; Oguri, Toyoko; Sato, Junko; Ogasawara, Kazuhiko; Wakamura, Tomotaro; Sunakawa, Keisuke; Watanabe, Akira; Iwata, Satoshi; Kaku, Mitsuo; Hanaki, Hideaki; Ohsaki, Yoshinobu; Watari, Tomohisa; Toyoshima, Eri; Takeuchi, Kenichi; Shiokoshi, Mayumi; Takeda, Hiroaki; Miki, Makoto; Kumagai, Toshio; Nakanowatari, Susumu; Takahashi, Hiroshi; Utagawa, Mutsuko; Nishiya, Hajime; Kawakami, Sayoko; Kobayashi, Nobuyuki; Takasaki, Jin; Mezaki, Kazuhisa; Konosaki, Hisami; Aoki, Yasuko; Yamamoto, Yumiko; Shoji, Michi; Goto, Hajime; Saraya, Takeshi; Kurai, Daisuke; Okazaki, Mitsuhiro; Niki, Yoshihito; Yoshida, Koichiro; Kawana, Akihiko; Saionji, Katsu; Fujikura, Yuji; Miyazawa, Naoki; Kudo, Makoto; Sato, Yoshimi; Yamamoto, Masaki; Yoshida, Takashi; Nakamura, Masahiko; Tsukada, Hiroki; Imai, Yumiko; Tsukada, Ayami; Kawasaki, Satoshi; Honma, Yasuo; Yamamoto, Toshinobu; Ban, Nobuyoshi; Mikamo, Hiroshige; Sawamura, Haruki; Miyara, Takayuki; Toda, Hirofumi; Sato, Kaori; Nakamura, Tadahiro; Fujikawa, Yasunori; Mitsuno, Noriko; Mikasa, Keiichi; Kasahara, Kei; Sano, Reiko; Sugimoto, Keisuke; Asari, Seishi; Nishi, Isao; Toyokawa, Masahiro; Miyashita, Naoyuki; Koguchi, Yutaka; Kusano, Nobuchika; Mihara, Eiichirou; Kuwabara, Masao; Watanabe, Yaeko; Kawasaki, Yuji; Takeda, Kenichi; Tokuyasu, Hirokazu; Masui, Kayoko; Negayama, Kiyoshi; Hiramatsu, Kazufumi; Aoki, Yosuke; Fukuoka, Mami; Magarifuchi, Hiroki; Nagasawa, Zenzo; Suga, Moritaka; Muranaka, Hiroyuki; Morinaga, Yoshitomo; Honda, Junichi; Fujita, Masaki.

In: Journal of Infection and Chemotherapy, Vol. 21, No. 6, 01.06.2015, p. 410-420.

Research output: Contribution to journalArticle

Yanagihara, K, Kadota, J, Aoki, N, Matsumoto, T, Yoshida, M, Yagisawa, M, Oguri, T, Sato, J, Ogasawara, K, Wakamura, T, Sunakawa, K, Watanabe, A, Iwata, S, Kaku, M, Hanaki, H, Ohsaki, Y, Watari, T, Toyoshima, E, Takeuchi, K, Shiokoshi, M, Takeda, H, Miki, M, Kumagai, T, Nakanowatari, S, Takahashi, H, Utagawa, M, Nishiya, H, Kawakami, S, Kobayashi, N, Takasaki, J, Mezaki, K, Konosaki, H, Aoki, Y, Yamamoto, Y, Shoji, M, Goto, H, Saraya, T, Kurai, D, Okazaki, M, Niki, Y, Yoshida, K, Kawana, A, Saionji, K, Fujikura, Y, Miyazawa, N, Kudo, M, Sato, Y, Yamamoto, M, Yoshida, T, Nakamura, M, Tsukada, H, Imai, Y, Tsukada, A, Kawasaki, S, Honma, Y, Yamamoto, T, Ban, N, Mikamo, H, Sawamura, H, Miyara, T, Toda, H, Sato, K, Nakamura, T, Fujikawa, Y, Mitsuno, N, Mikasa, K, Kasahara, K, Sano, R, Sugimoto, K, Asari, S, Nishi, I, Toyokawa, M, Miyashita, N, Koguchi, Y, Kusano, N, Mihara, E, Kuwabara, M, Watanabe, Y, Kawasaki, Y, Takeda, K, Tokuyasu, H, Masui, K, Negayama, K, Hiramatsu, K, Aoki, Y, Fukuoka, M, Magarifuchi, H, Nagasawa, Z, Suga, M, Muranaka, H, Morinaga, Y, Honda, J & Fujita, M 2015, 'Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010: General view of the pathogens' antibacterial susceptibility', Journal of Infection and Chemotherapy, vol. 21, no. 6, pp. 410-420. https://doi.org/10.1016/j.jiac.2015.02.008
Yanagihara, Katsunori ; Kadota, Junichi ; Aoki, Nobuki ; Matsumoto, Tetsuya ; Yoshida, Masaki ; Yagisawa, Morimasa ; Oguri, Toyoko ; Sato, Junko ; Ogasawara, Kazuhiko ; Wakamura, Tomotaro ; Sunakawa, Keisuke ; Watanabe, Akira ; Iwata, Satoshi ; Kaku, Mitsuo ; Hanaki, Hideaki ; Ohsaki, Yoshinobu ; Watari, Tomohisa ; Toyoshima, Eri ; Takeuchi, Kenichi ; Shiokoshi, Mayumi ; Takeda, Hiroaki ; Miki, Makoto ; Kumagai, Toshio ; Nakanowatari, Susumu ; Takahashi, Hiroshi ; Utagawa, Mutsuko ; Nishiya, Hajime ; Kawakami, Sayoko ; Kobayashi, Nobuyuki ; Takasaki, Jin ; Mezaki, Kazuhisa ; Konosaki, Hisami ; Aoki, Yasuko ; Yamamoto, Yumiko ; Shoji, Michi ; Goto, Hajime ; Saraya, Takeshi ; Kurai, Daisuke ; Okazaki, Mitsuhiro ; Niki, Yoshihito ; Yoshida, Koichiro ; Kawana, Akihiko ; Saionji, Katsu ; Fujikura, Yuji ; Miyazawa, Naoki ; Kudo, Makoto ; Sato, Yoshimi ; Yamamoto, Masaki ; Yoshida, Takashi ; Nakamura, Masahiko ; Tsukada, Hiroki ; Imai, Yumiko ; Tsukada, Ayami ; Kawasaki, Satoshi ; Honma, Yasuo ; Yamamoto, Toshinobu ; Ban, Nobuyoshi ; Mikamo, Hiroshige ; Sawamura, Haruki ; Miyara, Takayuki ; Toda, Hirofumi ; Sato, Kaori ; Nakamura, Tadahiro ; Fujikawa, Yasunori ; Mitsuno, Noriko ; Mikasa, Keiichi ; Kasahara, Kei ; Sano, Reiko ; Sugimoto, Keisuke ; Asari, Seishi ; Nishi, Isao ; Toyokawa, Masahiro ; Miyashita, Naoyuki ; Koguchi, Yutaka ; Kusano, Nobuchika ; Mihara, Eiichirou ; Kuwabara, Masao ; Watanabe, Yaeko ; Kawasaki, Yuji ; Takeda, Kenichi ; Tokuyasu, Hirokazu ; Masui, Kayoko ; Negayama, Kiyoshi ; Hiramatsu, Kazufumi ; Aoki, Yosuke ; Fukuoka, Mami ; Magarifuchi, Hiroki ; Nagasawa, Zenzo ; Suga, Moritaka ; Muranaka, Hiroyuki ; Morinaga, Yoshitomo ; Honda, Junichi ; Fujita, Masaki. / Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010 : General view of the pathogens' antibacterial susceptibility. In: Journal of Infection and Chemotherapy. 2015 ; Vol. 21, No. 6. pp. 410-420.
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abstract = "The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, was conducted by Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for Clinical Microbiology in 2010.The isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period from January and April 2010 by three societies. Antimicrobial susceptibility testing was conducted at the central reference laboratory according to the method recommended by Clinical and Laboratory Standard Institutes using maximum 45 antibacterial agents.Susceptibility testing was evaluable with 954 strains (206 Staphylococcus aureus, 189 Streptococcus pneumoniae, 4 Streptococcus pyogenes, 182 Haemophilus influenzae, 74 Moraxella catarrhalis, 139 Klebsiella pneumoniae and 160 Pseudomonas aeruginosa). Ratio of methicillin-resistant S.aureus was as high as 50.5{\%}, and those of penicillin-intermediate and -resistant S.pneumoniae were 1.1{\%} and 0.0{\%}, respectively. Among H.influenzae, 17.6{\%} of them were found to be β-lactamase-non-producing ampicillin (ABPC)-intermediately resistant, 33.5{\%} to be β-lactamase-non-producing ABPC-resistant and 11.0{\%} to be β-lactamase-producing ABPC-resistant strains. Extended spectrum β-lactamase-producing K.pneumoniae and multi-drug resistant P.aeruginosa with metallo β-lactamase were 2.9{\%} and 0.6{\%}, respectively.Continuous national surveillance of antimicrobial susceptibility of respiratory pathogens is crucial in order to monitor changing patterns of susceptibility and to be able to update treatment recommendations on a regular basis.",
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T1 - Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010

T2 - General view of the pathogens' antibacterial susceptibility

AU - Yanagihara, Katsunori

AU - Kadota, Junichi

AU - Aoki, Nobuki

AU - Matsumoto, Tetsuya

AU - Yoshida, Masaki

AU - Yagisawa, Morimasa

AU - Oguri, Toyoko

AU - Sato, Junko

AU - Ogasawara, Kazuhiko

AU - Wakamura, Tomotaro

AU - Sunakawa, Keisuke

AU - Watanabe, Akira

AU - Iwata, Satoshi

AU - Kaku, Mitsuo

AU - Hanaki, Hideaki

AU - Ohsaki, Yoshinobu

AU - Watari, Tomohisa

AU - Toyoshima, Eri

AU - Takeuchi, Kenichi

AU - Shiokoshi, Mayumi

AU - Takeda, Hiroaki

AU - Miki, Makoto

AU - Kumagai, Toshio

AU - Nakanowatari, Susumu

AU - Takahashi, Hiroshi

AU - Utagawa, Mutsuko

AU - Nishiya, Hajime

AU - Kawakami, Sayoko

AU - Kobayashi, Nobuyuki

AU - Takasaki, Jin

AU - Mezaki, Kazuhisa

AU - Konosaki, Hisami

AU - Aoki, Yasuko

AU - Yamamoto, Yumiko

AU - Shoji, Michi

AU - Goto, Hajime

AU - Saraya, Takeshi

AU - Kurai, Daisuke

AU - Okazaki, Mitsuhiro

AU - Niki, Yoshihito

AU - Yoshida, Koichiro

AU - Kawana, Akihiko

AU - Saionji, Katsu

AU - Fujikura, Yuji

AU - Miyazawa, Naoki

AU - Kudo, Makoto

AU - Sato, Yoshimi

AU - Yamamoto, Masaki

AU - Yoshida, Takashi

AU - Nakamura, Masahiko

AU - Tsukada, Hiroki

AU - Imai, Yumiko

AU - Tsukada, Ayami

AU - Kawasaki, Satoshi

AU - Honma, Yasuo

AU - Yamamoto, Toshinobu

AU - Ban, Nobuyoshi

AU - Mikamo, Hiroshige

AU - Sawamura, Haruki

AU - Miyara, Takayuki

AU - Toda, Hirofumi

AU - Sato, Kaori

AU - Nakamura, Tadahiro

AU - Fujikawa, Yasunori

AU - Mitsuno, Noriko

AU - Mikasa, Keiichi

AU - Kasahara, Kei

AU - Sano, Reiko

AU - Sugimoto, Keisuke

AU - Asari, Seishi

AU - Nishi, Isao

AU - Toyokawa, Masahiro

AU - Miyashita, Naoyuki

AU - Koguchi, Yutaka

AU - Kusano, Nobuchika

AU - Mihara, Eiichirou

AU - Kuwabara, Masao

AU - Watanabe, Yaeko

AU - Kawasaki, Yuji

AU - Takeda, Kenichi

AU - Tokuyasu, Hirokazu

AU - Masui, Kayoko

AU - Negayama, Kiyoshi

AU - Hiramatsu, Kazufumi

AU - Aoki, Yosuke

AU - Fukuoka, Mami

AU - Magarifuchi, Hiroki

AU - Nagasawa, Zenzo

AU - Suga, Moritaka

AU - Muranaka, Hiroyuki

AU - Morinaga, Yoshitomo

AU - Honda, Junichi

AU - Fujita, Masaki

PY - 2015/6/1

Y1 - 2015/6/1

N2 - The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, was conducted by Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for Clinical Microbiology in 2010.The isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period from January and April 2010 by three societies. Antimicrobial susceptibility testing was conducted at the central reference laboratory according to the method recommended by Clinical and Laboratory Standard Institutes using maximum 45 antibacterial agents.Susceptibility testing was evaluable with 954 strains (206 Staphylococcus aureus, 189 Streptococcus pneumoniae, 4 Streptococcus pyogenes, 182 Haemophilus influenzae, 74 Moraxella catarrhalis, 139 Klebsiella pneumoniae and 160 Pseudomonas aeruginosa). Ratio of methicillin-resistant S.aureus was as high as 50.5%, and those of penicillin-intermediate and -resistant S.pneumoniae were 1.1% and 0.0%, respectively. Among H.influenzae, 17.6% of them were found to be β-lactamase-non-producing ampicillin (ABPC)-intermediately resistant, 33.5% to be β-lactamase-non-producing ABPC-resistant and 11.0% to be β-lactamase-producing ABPC-resistant strains. Extended spectrum β-lactamase-producing K.pneumoniae and multi-drug resistant P.aeruginosa with metallo β-lactamase were 2.9% and 0.6%, respectively.Continuous national surveillance of antimicrobial susceptibility of respiratory pathogens is crucial in order to monitor changing patterns of susceptibility and to be able to update treatment recommendations on a regular basis.

AB - The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, was conducted by Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for Clinical Microbiology in 2010.The isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period from January and April 2010 by three societies. Antimicrobial susceptibility testing was conducted at the central reference laboratory according to the method recommended by Clinical and Laboratory Standard Institutes using maximum 45 antibacterial agents.Susceptibility testing was evaluable with 954 strains (206 Staphylococcus aureus, 189 Streptococcus pneumoniae, 4 Streptococcus pyogenes, 182 Haemophilus influenzae, 74 Moraxella catarrhalis, 139 Klebsiella pneumoniae and 160 Pseudomonas aeruginosa). Ratio of methicillin-resistant S.aureus was as high as 50.5%, and those of penicillin-intermediate and -resistant S.pneumoniae were 1.1% and 0.0%, respectively. Among H.influenzae, 17.6% of them were found to be β-lactamase-non-producing ampicillin (ABPC)-intermediately resistant, 33.5% to be β-lactamase-non-producing ABPC-resistant and 11.0% to be β-lactamase-producing ABPC-resistant strains. Extended spectrum β-lactamase-producing K.pneumoniae and multi-drug resistant P.aeruginosa with metallo β-lactamase were 2.9% and 0.6%, respectively.Continuous national surveillance of antimicrobial susceptibility of respiratory pathogens is crucial in order to monitor changing patterns of susceptibility and to be able to update treatment recommendations on a regular basis.

KW - Resistance

KW - Respiratory tract infection

KW - Surveillance

KW - Susceptibility

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