Abstract
Covering: up to 2015 The Wnt signalling pathway is essential in many biological processes. The Wnt signal is associated with several diseases, particularly cancer and neurodegenerative diseases. Recently, high-throughput screening systems have been developed to rapidly identify compounds, including natural compounds, that target the Wnt signal. Some studies on natural modulators of the Wnt signal have also suggested their possible target. This review highlights some important natural compounds reported to regulate Wnt activity and describes their possible mechanism of action.
| Original language | English |
|---|---|
| Pages (from-to) | 1622-1628 |
| Number of pages | 7 |
| Journal | Natural Product Reports |
| Volume | 32 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2015 Dec |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Fingerprint Dive into the research topics of 'Natural compounds with Wnt signal modulating activity'. Together they form a unique fingerprint.
Cite this
Fuentes, R. G., Arai, M. A., & Ishibashi, M. (2015). Natural compounds with Wnt signal modulating activity. Natural Product Reports, 32(12), 1622-1628. https://doi.org/10.1039/c5np00074b