TY - JOUR
T1 - Near-infrared spectroscopic measurement of fat in the myocardial optical phantom
AU - Hibi, Takuma
AU - Yasumoto, Keito
AU - Ogawa, Emiyu
AU - Arai, Tsunenori
PY - 2014/8/17
Y1 - 2014/8/17
N2 - We studied the relation between the fat ratio in optical phantoms and near-infrared spectrum for multivariate analysis to develop a detection method of ganglionated plexuses in epicardial fat under catheter intervention. The optical phantoms of human myocardial tissue were made from water, agar, and triglyceride. The spectrum of back-scattering light was measured by an optical fiber in water or pig blood. We investigated the relation between the fat ratio and peak areas, using spectrum in 1000~1500 nm, its 1st, and 2nd derivative spectrum. The determinated coefficients were 0.97 and 0.99, respectively. We obtained a method to estimate the fat ratio of optical phantoms [%] ex vivo with error under 1.99 and 1.37 [%], respectively. According to the publications and our results, we calculated epicardial fat thickness with an accuracy of 0.20 and 0.14 [mm], respectively. In conclusion, we predicted that we might detect ganglionated plexuses by measurement of the fat ratio in vivo.
AB - We studied the relation between the fat ratio in optical phantoms and near-infrared spectrum for multivariate analysis to develop a detection method of ganglionated plexuses in epicardial fat under catheter intervention. The optical phantoms of human myocardial tissue were made from water, agar, and triglyceride. The spectrum of back-scattering light was measured by an optical fiber in water or pig blood. We investigated the relation between the fat ratio and peak areas, using spectrum in 1000~1500 nm, its 1st, and 2nd derivative spectrum. The determinated coefficients were 0.97 and 0.99, respectively. We obtained a method to estimate the fat ratio of optical phantoms [%] ex vivo with error under 1.99 and 1.37 [%], respectively. According to the publications and our results, we calculated epicardial fat thickness with an accuracy of 0.20 and 0.14 [mm], respectively. In conclusion, we predicted that we might detect ganglionated plexuses by measurement of the fat ratio in vivo.
KW - Fat
KW - Ganglionated plexuses
KW - Near-infrared
KW - Phantom
KW - Spectroscopy
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U2 - 10.11239/jsmbe.52.O-454
DO - 10.11239/jsmbe.52.O-454
M3 - Article
AN - SCOPUS:84939459476
SN - 1347-443X
VL - 52
SP - O-454
JO - BME = Bio medical engineering / henshu, Nihon ME Gakkai
JF - BME = Bio medical engineering / henshu, Nihon ME Gakkai
ER -