Nematocidal Principles In “Oakmoss Absolute” and Nematocidal Activity of 2,4-Dihydroxybenzoates

Kaoru Kondo, Toshiya Sato, Ali Mohammad Ahad, Yoshihisa Goto, Fumiyuki Kiuchi, Yoshisuke Tsuda

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 μm).

Original languageEnglish
Pages (from-to)1043-1046
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume39
Issue number4
DOIs
Publication statusPublished - 1991

Keywords

  • Evernia prunastri
  • Toxocara canis
  • dihydroxybenzoate
  • nematocidal activity
  • oakmoss absolute
  • octyl 2,4-dihydroxybenzoate
  • structure-activity relationship

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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