New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

Rika Obata; Toshiaki Sunazuka; Zhiming Tian; Hiroshi Tomoda; Yoshihiro Harigaya; Satoshi Omura; Amos B. Smith

doi:10.1246/cl.1997.935

New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

Rika Obata, Toshiaki Sunazuka, Zhiming Tian, Hiroshi Tomoda, Yoshihiro Harigaya, Satoshi Omura, Amos B. Smith

Department of Humanities and Social Sciences

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

Original language	English
Pages (from-to)	935-936
Number of pages	2
Journal	Chemistry Letters
Issue number	9
DOIs	https://doi.org/10.1246/cl.1997.935
Publication status	Published - 1997 Jan 1

ASJC Scopus subject areas

Chemistry(all)

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title = "New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization",

abstract = "The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.",

author = "Rika Obata and Toshiaki Sunazuka and Zhiming Tian and Hiroshi Tomoda and Yoshihiro Harigaya and Satoshi Omura and Smith, {Amos B.}",

year = "1997",

month = jan,

day = "1",

doi = "10.1246/cl.1997.935",

language = "English",

pages = "935--936",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Chemical Society of Japan",

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T1 - New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

AU - Obata, Rika

AU - Sunazuka, Toshiaki

AU - Tian, Zhiming

AU - Tomoda, Hiroshi

AU - Harigaya, Yoshihiro

AU - Omura, Satoshi

AU - Smith, Amos B.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

AB - The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

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UR - http://www.scopus.com/inward/citedby.url?scp=0002715660&partnerID=8YFLogxK

U2 - 10.1246/cl.1997.935

DO - 10.1246/cl.1997.935

M3 - Article

AN - SCOPUS:0002715660

SN - 0366-7022

SP - 935

EP - 936

JO - Chemistry Letters

JF - Chemistry Letters

IS - 9

ER -

New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

Abstract

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