New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization

Rika Obata, Toshiaki Sunazuka, Zhiming Tian, Hiroshi Tomoda, Yoshihiro Harigaya, Satoshi Omura, Amos B. Smith

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

Original languageEnglish
Pages (from-to)935-936
Number of pages2
JournalChemistry Letters
Issue number9
DOIs
Publication statusPublished - 1997 Jan 1

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'New analogs of the pyripyropene family of ACAT inhibitors via α-pyrone fragmentation and γ-acylation/cyclization'. Together they form a unique fingerprint.

Cite this