New insight into reaction of iron(III)-peroxide adduct with alkanes: An alternative model for cytochrome P-450 and methane monooxygenase

Yuzo Nishida, Sayo Ito, Takashi Okuno, Shigeru Ohba

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A new mechanism for alkane functionalization by iron(III)-peroxide adducts was proposed, and the importance of electrophilic nature of the metal-peroxide adduct with η1-coordination mode was emphasized. This idea suggests that formation of high-valent iron-oxo species occurs most likely when the metal-peroxide intermediate is activated through electronic interaction with both the peripheral organic group and substrate; the latter two act as an electron donor to the peroxide adduct.

Original languageEnglish
Pages (from-to)615-622
Number of pages8
JournalZeitschrift fur Naturforschung Section C - Journal of Biosciences
Volume52
Issue number9-10
DOIs
Publication statusPublished - 1997

Keywords

  • Activation of Peroxide Adduct
  • Alkane Functionalization
  • Electrophilicity of Metal-peroxide
  • Iron(III)-peroxide Adduct

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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