New sentinel node mapping technologies for early gastric cancer

Hiroya Takeuchi, Yuukou Kitagawa

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

The sentinel node (SN) concept has revolutionized the surgical staging of both melanoma and breast cancer over the past two decades. The application of this concept can yield benefits for patients by preventing various complications related to unnecessary prophylactic regional lymph node dissection in patients with cancer-negative SNs. Clinical application of SN mapping in patients with early gastric cancer has been a controversial issue for years. However, a recent meta-analysis and a prospective multicenter trial of SN mapping for early gastric cancer have shown acceptable SN detection rates and accuracy of determination of lymph node status. For early stage gastric cancer such as cT1N0M0, for which a better prognosis can be achieved through conventional surgical approaches, the establishment of individualized, minimally invasive treatments that may retain the patients' quality of life should be the next surgical challenge. Although there are many unresolved technical issues, laparoscopic SN biopsy with laparoscopic minimized gastrectomy or endoscopic mucosal resection/endoscopic submucosal dissection has the potential to achieve this goal.

Original languageEnglish
Pages (from-to)522-532
Number of pages11
JournalAnnals of Surgical Oncology
Volume20
Issue number2
DOIs
Publication statusPublished - 2013 Feb

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Stomach Neoplasms
Technology
Gastrectomy
Lymph Node Excision
Multicenter Studies
Meta-Analysis
Melanoma
Lymph Nodes
Quality of Life
cyhalothrin
Breast Neoplasms
Biopsy
Neoplasms
Endoscopic Mucosal Resection
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

New sentinel node mapping technologies for early gastric cancer. / Takeuchi, Hiroya; Kitagawa, Yuukou.

In: Annals of Surgical Oncology, Vol. 20, No. 2, 02.2013, p. 522-532.

Research output: Contribution to journalArticle

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