New trends in cellular therapy

Hideyuki Okano; Doug Sipp

doi:10.1242/dev.192567

New trends in cellular therapy

Hideyuki Okano, Doug Sipp

Department of Physiology

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.

Original language	English
Article number	dev192567
Journal	Development (Cambridge)
Volume	147
Issue number	18
DOIs	https://doi.org/10.1242/dev.192567
Publication status	Published - 2020 Sep

Keywords

Cardiomyopathy
Diabetes
Parkinson's disease
Pluripotent stem cells
Regenerative therapy

ASJC Scopus subject areas

Molecular Biology
Developmental Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1242/dev.192567

Cite this

@article{0ecd400dc90c47cf8cbcc05f7f7f5804,

title = "New trends in cellular therapy",

abstract = "Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.",

keywords = "Cardiomyopathy, Diabetes, Parkinson's disease, Pluripotent stem cells, Regenerative therapy",

author = "Hideyuki Okano and Doug Sipp",

note = "Publisher Copyright: {\textcopyright} 2020. Published by The Company of Biologists Ltd",

year = "2020",

month = sep,

doi = "10.1242/dev.192567",

language = "English",

volume = "147",

journal = "Journal of Embryology and Experimental Morphology",

issn = "0950-1991",

publisher = "Company of Biologists Ltd",

number = "18",

}

TY - JOUR

T1 - New trends in cellular therapy

AU - Okano, Hideyuki

AU - Sipp, Doug

PY - 2020/9

Y1 - 2020/9

N2 - Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.

AB - Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.

KW - Cardiomyopathy

KW - Diabetes

KW - Parkinson's disease

KW - Pluripotent stem cells

KW - Regenerative therapy

UR - http://www.scopus.com/inward/record.url?scp=85091193148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85091193148&partnerID=8YFLogxK

U2 - 10.1242/dev.192567

DO - 10.1242/dev.192567

M3 - Review article

C2 - 32943426

AN - SCOPUS:85091193148

VL - 147

JO - Journal of Embryology and Experimental Morphology

JF - Journal of Embryology and Experimental Morphology

SN - 0950-1991

IS - 18

M1 - dev192567

ER -

New trends in cellular therapy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this