New trends in cellular therapy

Hideyuki Okano; Doug Sipp

doi:10.1242/dev.192567

New trends in cellular therapy

Hideyuki Okano, Doug Sipp

Department of Physiology

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.

Original language	English
Article number	dev192567
Journal	Development (Cambridge)
Volume	147
Issue number	18
DOIs	https://doi.org/10.1242/dev.192567
Publication status	Published - 2020 Sep

Keywords

Cardiomyopathy
Diabetes
Parkinson's disease
Pluripotent stem cells
Regenerative therapy

ASJC Scopus subject areas

Molecular Biology
Developmental Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1242/dev.192567

Cite this

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abstract = "Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.",

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author = "Hideyuki Okano and Doug Sipp",

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AB - Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.

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KW - Parkinson's disease

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KW - Regenerative therapy

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New trends in cellular therapy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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