Newly developed fusogenic liposome

J. Sunamoto, K. Akiyoshi, K. Tanaka, T. Sato

Research output: Contribution to journalConference article

10 Citations (Scopus)

Abstract

Liposome has been widely utilized as a vehicle for delivering various substances such as DNA, RNA, enzymes, proteins, metabolites, or pharmaceutical drugs into various cells. For internalization of liposomes into cells, two possible paths have been considered; namely, phagocytosis (or endocytosis) and fusion. However, all previous methods still have several disadvantages. In order to overcome these disadvantages, we have designed a fusogenic liposome as prepared by mixing simple egg phosphatidylchloline and an artificial lipid, 2-[ω-hydroxy(oxyethylene)-α-yl]-1,3-bis-(dodecyloxy) propane and investigated the fusion between the fusogenic liposomes and carrot protoplasts.

Original languageEnglish
Pages (from-to)155-156
Number of pages2
JournalAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume31
Issue number2
Publication statusPublished - 1990 Aug 1
Externally publishedYes
EventPapers presented at the Washington, DC Meeting 1990 of the ACS, Division of Polymer Chemistry - Washington, DC, USA
Duration: 1990 Aug 261990 Aug 31

ASJC Scopus subject areas

  • Materials Science(all)
  • Polymers and Plastics
  • Engineering(all)

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