NKT cell frequency in Japanese type 1 diabetes

Yoichi Oikawa, Akira Shimada, Satoru Yamada, Yoshiko Motohashi, Yoshinori Nakagawa, Junichiro Irie, Taro Maruyama, Takao Saruta

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A numerical and functional deficit of natural killer T (NKT) cells has been reported to be associated with the pathogenesis of Caucasian patients with type 1 diabetes. However, a conflicting finding of a higher frequency of NKT cells (Valpha24+ Vbeta11+ T cells) was observed in Islet-associated Ab+ and Ab- Japanese "classic" type 1 diabetes. Here, we combined the data of NKT cell frequency in Ab+ and Ab- "classic" type 1 diabetic patients and then analyzed the relationship between NKT cell frequency and disease activity.

Original languageEnglish
Pages (from-to)230-232
Number of pages3
JournalAnnals of the New York Academy of Sciences
Volume1005
DOIs
Publication statusPublished - 2003

Fingerprint

Natural Killer T-Cells
T-cells
Medical problems
Type 1 Diabetes Mellitus
T-Lymphocytes
Diabetes
Cells

Keywords

  • NKT cell
  • Type 1 diabetes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Oikawa, Y., Shimada, A., Yamada, S., Motohashi, Y., Nakagawa, Y., Irie, J., ... Saruta, T. (2003). NKT cell frequency in Japanese type 1 diabetes. Annals of the New York Academy of Sciences, 1005, 230-232. https://doi.org/10.1196/annals.1288.033

NKT cell frequency in Japanese type 1 diabetes. / Oikawa, Yoichi; Shimada, Akira; Yamada, Satoru; Motohashi, Yoshiko; Nakagawa, Yoshinori; Irie, Junichiro; Maruyama, Taro; Saruta, Takao.

In: Annals of the New York Academy of Sciences, Vol. 1005, 2003, p. 230-232.

Research output: Contribution to journalArticle

Oikawa, Y, Shimada, A, Yamada, S, Motohashi, Y, Nakagawa, Y, Irie, J, Maruyama, T & Saruta, T 2003, 'NKT cell frequency in Japanese type 1 diabetes', Annals of the New York Academy of Sciences, vol. 1005, pp. 230-232. https://doi.org/10.1196/annals.1288.033
Oikawa, Yoichi ; Shimada, Akira ; Yamada, Satoru ; Motohashi, Yoshiko ; Nakagawa, Yoshinori ; Irie, Junichiro ; Maruyama, Taro ; Saruta, Takao. / NKT cell frequency in Japanese type 1 diabetes. In: Annals of the New York Academy of Sciences. 2003 ; Vol. 1005. pp. 230-232.
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