NKT cell frequency in Japanese type 1 diabetes

Yoichi Oikawa, Akira Shimada, Satoru Yamada, Yoshiko Motohashi, Yoshinori Nakagawa, Jun Ichiro Irie, Taro Maruyama, Takao Saruta

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

A numerical and functional deficit of natural killer T (NKT) cells has been reported to be associated with the pathogenesis of Caucasian patients with type 1 diabetes. However, a conflicting finding of a higher frequency of NKT cells (Valpha24+ Vbeta11+ T cells) was observed in Islet-associated Ab+ and Ab- Japanese "classic" type 1 diabetes. Here, we combined the data of NKT cell frequency in Ab+ and Ab- "classic" type 1 diabetic patients and then analyzed the relationship between NKT cell frequency and disease activity.

Original languageEnglish
Pages (from-to)230-232
Number of pages3
JournalAnnals of the New York Academy of Sciences
Volume1005
DOIs
Publication statusPublished - 2003 Jan 1

Keywords

  • NKT cell
  • Type 1 diabetes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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