Abstract
N,N-Dimethylformamide (DMF, CAS 68-12-2) is known to be one of the water-soluble organic solvents with a markedly high skin absorption rate. In volunteer exposure experiments of DMF vapor in laboratories, the proportions of the skin absorption to the total absorption were reported to be 14-39% 1), 13-39% 2), and 22-70% 3). However, it may not be appropriate to simply extrapolate these results to the working population, because working conditions influencing DMF vapor absorption, for example, temperature, humidity, physical activity, etc., are quite different from those of the volunteer laboratory exposure experiments. This study aimed to clarify the significance of the skin absorption of DMF vapor at worksites.
| Original language | English |
|---|---|
| Pages (from-to) | 92-94 |
| Number of pages | 3 |
| Journal | Journal of Occupational Health |
| Volume | 43 |
| Issue number | 2 |
| Publication status | Published - 2001 |
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Keywords
- Biological monitoring
- N,N-Dimethylformamide
- N-Methylformamide
- Skin absorption
- Volunteer
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Toxicology
Cite this
N,N-dimethylformamide (dmf) vapor absorption through the skin in workers. / Miyauchi, Hiroyuki; Tanaka, Shigeru; Nomiyama, Tetsuo; Seki, Yukio; Imamiya, Shun'ichiro; Omae, Kazuyuki.
In: Journal of Occupational Health, Vol. 43, No. 2, 2001, p. 92-94.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - N,N-dimethylformamide (dmf) vapor absorption through the skin in workers
AU - Miyauchi, Hiroyuki
AU - Tanaka, Shigeru
AU - Nomiyama, Tetsuo
AU - Seki, Yukio
AU - Imamiya, Shun'ichiro
AU - Omae, Kazuyuki
PY - 2001
Y1 - 2001
N2 - N,N-Dimethylformamide (DMF, CAS 68-12-2) is known to be one of the water-soluble organic solvents with a markedly high skin absorption rate. In volunteer exposure experiments of DMF vapor in laboratories, the proportions of the skin absorption to the total absorption were reported to be 14-39% 1), 13-39% 2), and 22-70% 3). However, it may not be appropriate to simply extrapolate these results to the working population, because working conditions influencing DMF vapor absorption, for example, temperature, humidity, physical activity, etc., are quite different from those of the volunteer laboratory exposure experiments. This study aimed to clarify the significance of the skin absorption of DMF vapor at worksites.
AB - N,N-Dimethylformamide (DMF, CAS 68-12-2) is known to be one of the water-soluble organic solvents with a markedly high skin absorption rate. In volunteer exposure experiments of DMF vapor in laboratories, the proportions of the skin absorption to the total absorption were reported to be 14-39% 1), 13-39% 2), and 22-70% 3). However, it may not be appropriate to simply extrapolate these results to the working population, because working conditions influencing DMF vapor absorption, for example, temperature, humidity, physical activity, etc., are quite different from those of the volunteer laboratory exposure experiments. This study aimed to clarify the significance of the skin absorption of DMF vapor at worksites.
KW - Biological monitoring
KW - N,N-Dimethylformamide
KW - N-Methylformamide
KW - Skin absorption
KW - Volunteer
UR - http://www.scopus.com/inward/record.url?scp=0035040802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035040802&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0035040802
VL - 43
SP - 92
EP - 94
JO - Journal of Occupational Health
JF - Journal of Occupational Health
SN - 1341-9145
IS - 2
ER -