N,N-dimethylformamide (dmf) vapor absorption through the skin in workers

Hiroyuki Miyauchi; Shigeru Tanaka; Tetsuo Nomiyama; Yukio Seki; Shun'ichiro Imamiya; Kazuyuki Omae

doi:10.1539/joh.43.92

N,N-dimethylformamide (dmf) vapor absorption through the skin in workers

Hiroyuki Miyauchi, Shigeru Tanaka, Tetsuo Nomiyama, Yukio Seki, Shun'ichiro Imamiya, Kazuyuki Omae

Department of Preventive Medicine and Public Health

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

N,N-Dimethylformamide (DMF, CAS 68-12-2) is known to be one of the water-soluble organic solvents with a markedly high skin absorption rate. In volunteer exposure experiments of DMF vapor in laboratories, the proportions of the skin absorption to the total absorption were reported to be 14-39%¹⁾, 13-39%²⁾, and 22-70%³⁾. However, it may not be appropriate to simply extrapolate these results to the working population, because working conditions influencing DMF vapor absorption, for example, temperature, humidity, physical activity, etc., are quite different from those of the volunteer laboratory exposure experiments. This study aimed to clarify the significance of the skin absorption of DMF vapor at worksites.

Original language	English
Pages (from-to)	92-94
Number of pages	3
Journal	Journal of occupational health
Volume	43
Issue number	2
DOIs	https://doi.org/10.1539/joh.43.92
Publication status	Published - 2001 Jan 1

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Keywords

Biological monitoring
N,N-Dimethylformamide
N-Methylformamide
Skin absorption
Volunteer

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

Cite this

Miyauchi, H., Tanaka, S., Nomiyama, T., Seki, Y., Imamiya, S., & Omae, K. (2001). N,N-dimethylformamide (dmf) vapor absorption through the skin in workers. Journal of occupational health, 43(2), 92-94. https://doi.org/10.1539/joh.43.92

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10.1539/joh.43.92