No more sugar-coating it: Mucins and platelet biology

Yumiko Matsubara

Research output: Contribution to journalReview article

Abstract

In this issue of Blood, Kudo et al demonstrate a critical role for mucin-type O-glycans in terminal differentiation of megakaryocytes and platelet release, using conditional knockout mouse for the catalytic enzyme for O-glycosylation. This article provides a model for understanding what role such near ubiquitous modifiers may have in terminal hematopoietic differentiation.

Original languageEnglish
Pages (from-to)1537-1538
Number of pages2
JournalBlood
Volume122
Issue number9
DOIs
Publication statusPublished - 2013 Aug 29

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ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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