Abstract
In this issue of Blood, Kudo et al demonstrate a critical role for mucin-type O-glycans in terminal differentiation of megakaryocytes and platelet release, using conditional knockout mouse for the catalytic enzyme for O-glycosylation. This article provides a model for understanding what role such near ubiquitous modifiers may have in terminal hematopoietic differentiation.
Original language | English |
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Pages (from-to) | 1537-1538 |
Number of pages | 2 |
Journal | Blood |
Volume | 122 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2013 Aug 29 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Immunology
- Hematology
- Cell Biology