A diversity scheme with Fractional Sampling (FS) in OFDM receivers has been investigated recently. FS path diversity makes use of imaging components of a desired signal transmitted on an adjacent channel. In the previous literature, a non-orthogonal access scheme over multiple channels with iterative interference cancellation (IIC) and FS was proposed. The conventional scheme has shown that the imaging component is transmitted non-orthogonally and path diversity is realized with FS and IIC. However, the conventional scheme does not take into account a spatial multiplexing transmission scheme such as multiple-input multiple-output (MIMO). Therefore, this paper proposes a MIMO-FS scheme with IIC and evaluates its performance through computer simulation. It is shown that in the MIMO situation with channel coding the proposed system improves the performance by 1.5dB at the BER of 10 -5 compared to a system without imaging components.