Nonhuman primate research in uterus transplantation

Iori Kisu; Yusuke Matoba; Kouji Banno; Daisuke Aoki

doi:10.1007/978-3-319-94162-2_7

Nonhuman primate research in uterus transplantation

Iori Kisu, Yusuke Matoba, Kouji Banno, Daisuke Aoki

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Uterus transplantation (UTx) is considered to be a possible approach for women with uterine factor infertility. Clinical research on this procedure has begun in several countries, but UTx is still at the experimental stage and many medical and technical issues remain to be resolved. UTx studies have been performed in many animal species, but further basic studies in animals are needed for accumulation of data that will allow further establishment of UTx, as a safe procedure in humans. In particular, validation using nonhuman primates that are physiologically and anatomically similar to humans is important for extrapolation to humans. In this chapter, the current status of research on UTx in nonhuman primates is summarized.

Original language	English
Title of host publication	Uterus Transplantation
Publisher	Springer International Publishing
Pages	57-67
Number of pages	11
ISBN (Electronic)	9783319941622
ISBN (Print)	9783319941615
DOIs	https://doi.org/10.1007/978-3-319-94162-2_7
Publication status	Published - 2019 Jan 1

ASJC Scopus subject areas

Health Professions(all)
Medicine(all)

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10.1007/978-3-319-94162-2_7

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abstract = "Uterus transplantation (UTx) is considered to be a possible approach for women with uterine factor infertility. Clinical research on this procedure has begun in several countries, but UTx is still at the experimental stage and many medical and technical issues remain to be resolved. UTx studies have been performed in many animal species, but further basic studies in animals are needed for accumulation of data that will allow further establishment of UTx, as a safe procedure in humans. In particular, validation using nonhuman primates that are physiologically and anatomically similar to humans is important for extrapolation to humans. In this chapter, the current status of research on UTx in nonhuman primates is summarized.",

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AU - Aoki, Daisuke

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AB - Uterus transplantation (UTx) is considered to be a possible approach for women with uterine factor infertility. Clinical research on this procedure has begun in several countries, but UTx is still at the experimental stage and many medical and technical issues remain to be resolved. UTx studies have been performed in many animal species, but further basic studies in animals are needed for accumulation of data that will allow further establishment of UTx, as a safe procedure in humans. In particular, validation using nonhuman primates that are physiologically and anatomically similar to humans is important for extrapolation to humans. In this chapter, the current status of research on UTx in nonhuman primates is summarized.

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Nonhuman primate research in uterus transplantation

Abstract

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