Novel acyl α-pyronoids, dictyopyrone A, B, and C, from Dictyostelium cellular slime molds

Yoshiaki Takaya, Haruhisa Kikuchi, Yuichi Terui, Jun Komiya, Ken Ichi Furukawa, Kazuhiko Seya, Shigeru Motomura, Akira Ito, Yoshiteru Oshima

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)

Abstract

For the elucidation of the diversity of secondary metabolites of Dictyostelium cellular slime molds, we investigate the constituent of three species of slime molds. From the methanol extract of their fruit bodies, we obtained three novel compounds, dictyopyrone A (1) and B (2) from D. discoideum and D. rhizoposium and dictyopyrone C (3) from D. longosporum. They possess a unique α-pyrone moiety with a side chain at the C-3 position. Their relative structures were elucidated by spectral means, and the absolute configuration was confirmed by asymmetric synthesis of 1. Since these compounds were obtained from different species of Dictyostelium slime molds, they may be a type of compound common to this genus.

Original languageEnglish
Pages (from-to)985-989
Number of pages5
JournalJournal of Organic Chemistry
Volume65
Issue number4
DOIs
Publication statusPublished - 2000 Feb 25
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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